ArticleInflammation2017
The Anti-inflammatory Activities of Two Major Withanolides from Physalis minima Via Acting on NF-κB, STAT3, and HO-1 in LPS-Stimulated RAW264.7 Cells.
Article in Inflammation, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 51 citations in OpenAlex.
- Exploring the Active Substances and Mechanism of Physalis Calyx seu Fructus Against Inflammation-related Respiratory Diseases via Integrating Ultra-Performance Liquid Chromatography-Tandem Mass Spectrometry, Network Pharmacological Analysis, and Experimental Verification.Chemistry & biodiversity · 2026Article
- Metabolic Profiling of Fermented Products of the Ethanolic Extract ofAntioxidants (Basel, Switzerland) · 2025Article
- In Vitro Culture ofInternational journal of genomics · 2025Article
- Withametelin inhibits TGF-β induced Epithelial-to-Mesenchymal Transition and Programmed-Death Ligand-1 expressionFrontiers in oncology · 2024Article
- Ethanol Extract ofMolecules (Basel, Switzerland) · 2023Article
- Phytochemical and biological review ofFuture science OA · 2023Review
- Recent Advances in the Chemistry and Therapeutic Evaluation of Naturally Occurring and Synthetic Withanolides.Molecules (Basel, Switzerland) · 2022Review
- Protective Effect of Brassica napus L. Hydrosols against Inflammation Response in RAW 264.7 Cells.Chinese journal of integrative medicine · 2021Article
- Article
- Anti-Inflammatory Effects of the Fraction from the Leaves ofEvidence-based complementary and alternative medicine : eCAM · 2021Article
- Astilbe Chinensis ethanol extract suppresses inflammation in macrophages via NF-κB pathway.BMC complementary medicine and therapies · 2020Article
- Bioactive A-ring rearranged limonoids from the root barks ofActa pharmaceutica Sinica. B · 2019Article
- Development of Species-Specific SCAR Markers, Based on a SCoT Analysis, to AuthenticateFrontiers in genetics · 2018Article
- Polydatin reduces Staphylococcus aureus lipoteichoic acid-induced injury by attenuating reactive oxygen species generation and TLR2-NFκB signalling.Journal of cellular and molecular medicine · 2017Article
- Thrombospondin-1 Production Regulates the Inflammatory Cytokine Secretion in THP-1 Cells Through NF-κB Signaling Pathway.Inflammation · 2017Article
- Pinus densiflora needle supercritical fluid extract suppresses the expression of pro-inflammatory mediators iNOS, IL-6 and IL-1β, and activation of inflammatory STAT1 and STAT3 signaling proteins in bacterial lipopolysaccharide-challenged murine macrophages.Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences · 2017Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Physalis minima has been traditionally used as a folk herbal medicine in China for the treatment of many inflammatory diseases. However, little is known about its anti-inflammatory constituents and associated molecular mechanisms. In our study, withaphysalin A (WA) and 2, 3-dihydro-withaphysalin C (WC), two major withanolide-type compounds, were obtained from the anti-inflammatory fraction of P. minima. Both WA and WC significantly inhibited the production of nitrite oxide (NO), prostaglandin E
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