Evidence map›Paper›PMID 27913675›Full record

ReviewBiochemical Society transactions2016

Motility and adhesion through type IV pili in Gram-positive bacteria.

Kurt H Piepenbrink, Eric J Sundberg

Open access · greenAbstract readReview
In one paragraph

Review in Biochemical Society transactions, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 88 citations in OpenAlex.

  1. Role of cell-associated and secretion-independent virulence factors of Pseudomonas aeruginosa in microbial keratitis and anti-virulence therapeutic strategies.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Electron Cryo-Tomography Reveals thebioRxiv : the preprint server for biology · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Type IV Pilus-Mediated Inhibition ofMicrobiology spectrum · 2023
    Article
  15. Article
  16. Microorganisms · 2023
    Article
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 2 countries.

Kurt H PiepenbrinkInstitute of Human Virology, University of Maryland School of Medicine, Baltimore, MD 21201, U.S.A.
Eric J SundbergInstitute of Human Virology, University of Maryland School of Medicine, Baltimore, MD 21201, U.S.A.
University of Maryland, Baltimore · US

Funding

Signaling Pathways in Innate ImmunityT32AI095190 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI Stefanie N. Vogel · 2012 to 2026
$4.7M
Structure & Function of Clostridium difficile Type IV PiliR01AI114902 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI SUNDBERG, ERIC JOHN · 2015 to 2019
$2.6M
Structural Basis of Type IV Pilus-Induced Clostridium difficile Microcolony FormationK22AI123467 · NIAID · UNIVERSITY OF NEBRASKA LINCOLN · PI PIEPENBRINK, KURT HENRY · 2017 to 2018
$260k
Structure and Function of Type IV Pili in Clostridium difficileF32AI110045 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI PIEPENBRINK, KURT HENRY · 2014 to 2015
$109k
NIAID NIH HHS F32 AI110045NIAID NIH HHS K22 AI123467NIAID NIH HHS R01 AI114902NIAID NIH HHS T32 AI095190
6 · The paper itself

Abstract

Type IV pili are hair-like bacterial surface appendages that play a role in diverse processes such as cellular adhesion, colonization, twitching motility, biofilm formation, and horizontal gene transfer. These extracellular fibers are composed exclusively or primarily of many copies of one or more pilin proteins, tightly packed in a helix so that the highly hydrophobic amino-terminus of the pilin is buried in the pilus core. Type IV pili have been characterized extensively in Gram-negative bacteria, and recent advances in high-throughput genomic sequencing have revealed that they are also widespread in Gram-positive bacteria. Here, we review the current state of knowledge of type IV pilus systems in Gram-positive bacterial species and discuss them in the broader context of eubacterial type IV pili.

Indexed as

Bacterial AdhesionFimbriae, BacterialFimbriae ProteinsGram-Positive BacteriaModels, MolecularMovementMutationProtein DomainsSpecies SpecificityFimbriae ProteinscrystallographyGram-positive bacteriatype IV pili

Identifiers

PMID27913675
PMCPMC5830096
OpenAlexW2558883735

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.