ReviewHematology. American Society of Hematology. Education Program2016
Risk stratification and management of acute pulmonary embolism.
Review in Hematology. American Society of Hematology. Education Program, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Who cites it
31 citing papers in PubMed, 57 citations in OpenAlex.
- A Case of Large Bilateral Pulmonary Embolism Presenting Only With Dyspnea in a Primary Care Clinic.Cureus · 2026Article
- Cancer-Associated Pulmonary Embolism in Contemporary Clinical Practice: Clinical Severity, Incidental Detection, and Early Outcomes in a Real-World Cohort.Journal of clinical medicine · 2026Article
- Beyond the clot: diagnostic yield, biomarker performance, and the landscape of alternative diagnoses in emergency CT pulmonary angiography.Emergency radiology · 2026Article
- Thromboinflammation and hemostatic activation drive early mortality risk in pulmonary embolism.Research and practice in thrombosis and haemostasis · 2026Article
- Bypassing D-dimer Testing in Suspected High-Risk Pulmonary Embolism in the Emergency Department: A Case Report.Cureus · 2026Article
- Sivelestat sodium mitigates lung injury post-acute pulmonary embolism by inhibiting NE-SPP1 neutrophil recruitment and restoring redox balance.Scientific reports · 2026Article
- Pulmonary embolism consensus.Archivos de cardiologia de Mexico · 2026Article
- Case Report: Postoperative pulmonary embolism causing obstructive shock and circulatory collapse after gynecologic surgery: successful rescue with VA-ECMO.Frontiers in cardiovascular medicine · 2026Article
- What the Interventional Radiologist Needs to Know about Imaging Studies for the Detection, Risk Stratification, and Short- and Long-Term Follow-up of Pulmonary Embolism.Seminars in interventional radiology · 2025Review
- An Exploratory Research to Evaluate the 30 Most Common Pulmonary Embolism Drugs in the Food and Drug Administration Adverse Event Reporting System.The clinical respiratory journal · 2025Article
- Practice Patterns and Outcomes of Initial Anticoagulation Among Hospitalized Patients With Low- and Low-Intermediate-Risk Pulmonary Embolism.CHEST pulmonary · 2025Article
- Retrospective analysis of the occurrence, potential risk factors and medical significance of pulmonary complications after total shoulder arthroplasty from the National Inpatient Sample database (2010-2019).Perioperative medicine (London, England) · 2025Article
- Research progress on the association between lung cancer and pulmonary embolism.Journal of cardiothoracic surgery · 2025Review
- A functionalized method for assessing the risk of adverse events in patients with pulmonary embolism.Frontiers in medicine · 2025Article
- Risk factors for pulmonary embolism in malignant tumors patients with lower limb deep vein thrombosis: a retrospective study.American journal of cancer research · 2025Article
- Hospital Zambrano Hellion pulmonary embolism response team: PERT-PREVENTION.Archivos de cardiologia de Mexico · 2025Article
- Article
- Characteristics of patients with symptomatic and incidental pulmonary thromboembolism.Tuberkuloz ve toraks · 2024Article
- Association between statin use and acute pulmonary embolism in intensive care unit patients with sepsis: a retrospective cohort study.Frontiers in medicine · 2024Article
- Surgical pulmonary embolectomy: state of the art.Kardiochirurgia i torakochirurgia polska = Polish journal of cardio-thoracic surgery · 2023Review
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The clinical management of patients with acute pulmonary embolism is rapidly changing over the years. The widening spectrum of clinical management strategies for these patients requires effective tools for risk stratification. Patients at low risk for death could be candidates for home treatment or early discharge. Clinical models with high negative predictive value have been validated that could be used to select patients at low risk for death. In a major study and in several meta-analyses, thrombolysis in hemodynamically stable patients was associated with unacceptably high risk for major bleeding complications or intracranial hemorrhage. Thus, the presence of shock or sustained hypotension continues to be the criterion for the selection of candidates for thrombolytic treatment. Interventional procedures for early revascularization should be reserved to selected patients until further evidence is available. No clinical advantage is expected with the insertion of a vena cava filter in the acute-phase management of patients with acute pulmonary embolism. Direct oral anticoagulants used in fixed doses without laboratory monitoring showed similar efficacy (odds ratio [OR], 0.89; 95% confidence interval [CI], 0.70-1.12) and safety (OR, 0.89; 95% CI, 0.77-1.03) in comparison with conventional anticoagulation in patients with acute pulmonary embolism. Based on these results and on their practicality, direct oral anticoagulants are the agents of choice for the treatment of the majority of patients with acute pulmonary embolism.
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