Evidence map›Paper›PMID 27913425›Full record

ArticleAmerican journal of physiology. Lung cellular and molecular physiology2017

CD36 mediates H2O2-induced calcium influx in lung microvascular endothelial cells.

Karthik Suresh, Laura Servinsky, Jose Reyes, Clark Undem, Joel Zaldumbide, Otgonchimeg Rentsendorj, Sruti Modekurty, Jeffrey M Dodd-O, Alan Scott, David B Pearse and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in American journal of physiology. Lung cellular and molecular physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Reactive Oxygen Species and Endothelial CaInternational journal of molecular sciences · 2021
    Review
  14. Review
  15. Toxins · 2021
    Review
  16. Integrative Role of Albumin: Evolutionary, Biochemical and Pathophysiological Aspects.Journal of evolutionary biochemistry and physiology · 2021
    Article
  17. Review
  18. The clearance of dead cells by efferocytosis.Nature reviews. Molecular cell biology · 2020
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Karthik SureshDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland; ksuresh2@jhmi.edu.
Laura ServinskyDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Jose ReyesDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Clark UndemDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Joel ZaldumbideDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Otgonchimeg RentsendorjDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Sruti ModekurtyDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Jeffrey M Dodd-ODepartment of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland; and.
Alan ScottDepartment of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.
David B PearseDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Larissa A ShimodaDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Johns Hopkins University · USJohns Hopkins Medicine · US

Funding

MULTIDISCIPLINARY TRAINING PROGRAM IN LUNG DISEASEST32HL007534 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI Nadia N Hansel, Larissa A. Shimoda · 1985 to 2026
$28.3M
Na+/H+ exchange in pulmonary hypertensionR01HL073859 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI SHIMODA, LARISSA A. · 2003 to 2020
$4.2M
Short-Term Training Program to Increase Diversity in Health-Related ResearchR25HL084762 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI DAMARLA, MAHENDRA, SHIMODA, LARISSA A. · 2006 to 2024
$2.1M
Role of CD36 in ROS induced Ca influx in lung microvascular endothelial cellsF32HL124930 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI SURESH, KARTHIK · 2014 to 2015
$116k
NHLBI NIH HHS F32 HL124930NHLBI NIH HHS R01 HL073859NHLBI NIH HHS R25 HL084762NHLBI NIH HHS T32 HL007534
6 · The paper itself

Abstract

Elevated levels of reactive oxygen species and intracellular Ca

Indexed as

AnimalsCalciumCD36 AntigensEndothelial CellsFatty AcidsGene DeletionHydrogen PeroxideLipoproteins, LDLLungMice, Inbred C57BLMicrovesselsOleic AcidPhosphorylationProtein BindingProtein TransportProto-Oncogene Proteins c-fynacetyl-LDLCalciumCD36 AntigensFatty AcidsFyn protein, mouseHydrogen PeroxideLipoproteins, LDLOleic AcidProto-Oncogene Proteins c-fynTrpv4 protein, mouseTRPV Cation Channelsacute lung injurycalciumROS

Identifiers

PMID27913425
PMCPMC5283925
OpenAlexW2558197525

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.