ArticleBrazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]
Biofilm production and beta-lactamic resistance in Brazilian Staphylococcus aureus isolates from bovine mastitis.
Article in Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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27 citing papers in PubMed.
- Review
- Antimicrobial susceptibility, molecular characterization and multilocus sequence typing of Staphylococcus aureus isolates associated with subclinical mastitis in buffaloes (Bubalus bubalis) in Haryana, India.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026Article
- Genetic and Phenotypic Characteristics of FiveAnimals : an open access journal from MDPI · 2026Article
- Nanoparticles as an alternative treatment for bovine mastitis-A review.Animal bioscience · 2025Article
- Polyhexamethylene Biguanide Nanoparticles Inhibit Biofilm Formation by Mastitis-CausingVeterinary sciences · 2025Article
- Article
- Antimicrobial therapy approaches in the mastitis control driven by one health insights.Brazilian journal of veterinary medicine · 2024Article
- Exploration ofFrontiers in cellular and infection microbiology · 2024Article
- Genetic and Phenotypic Characterization of Subclinical Mastitis-Causing Multidrug-ResistantAntibiotics (Basel, Switzerland) · 2023Article
- Antimicrobial susceptibility of bovine clinical mastitis pathogens in Japan and development of a simplified agar disk diffusion method for clinical practice.The Journal of veterinary medical science · 2023Article
- Biofilm forming multidrug resistantIranian journal of veterinary research · 2023Article
- Prevalence and virulence genes ofPeerJ · 2023Article
- Antibioflm effects of extracellular matrix degradative agents on the biofilm of different strains of multi-drug resistant Corynebacterium striatum.Annals of clinical microbiology and antimicrobials · 2022Article
- Persistence of Staphylococcus spp. in milk from cows undergoing homeopathy to control subclinical mastitis.BMC veterinary research · 2022Article
- Comparative genomic analysis ofMicrobial genomics · 2022Article
- Relationship between Biofilm Formation and Antibiotic Resistance and Adherence Genes inInternational journal of microbiology · 2022Article
- Down-regulation of biofilm-associated genes in mecA-positive methicillin-resistant S. aureus treated with M. communis extract and its antibacterial activity.AMB Express · 2021Article
- Virulence Factors inAntibiotics (Basel, Switzerland) · 2021Article
- Biotechnological Potential of Eugenol and Thymol Derivatives Against Staphylococcus aureus from Bovine Mastitis.Current microbiology · 2021Article
- Virulence factors and antimicrobial resistance in Staphylococcus aureus isolated from bovine mastitis in Brazil.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2020Article
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8 authors.
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Abstract
Staphylococcus spp. play an important role in the etiology of bovine mastitis. Staphylococcus aureus is considered the most relevant species due to the production of virulence factors such as slime, which is required for biofilm formation. This study aimed to evaluate biofilm production and its possible relation to beta-lactamic resistance in 20 S. aureus isolates from bovine mastitic milk. The isolates were characterized by pheno-genotypic and MALDI TOF-MS assays and tested for genes such as icaA, icaD, bap, agr RNAIII, agr I, agr II, agr III, and agr IV, which are related to slime production and its regulation. Biofilm production in microplates was evaluated considering the intervals determined along the bacterial growth curve. In addition, to determine the most suitable time interval for biofilm analysis, scanning electron microscopy was performed. Furthermore, genes such as mecA and blaZ that are related to beta-lactamic resistance and oxacillin susceptibility were tested. All the studied isolates were biofilm producers and mostly presented icaA and icaD. The Agr type II genes were significantly prevalent. According to the SEM, gradual changes in the bacterial arrangement were observed during biofilm formation along the growth curve phases, and the peak was reached at the stationary phase. In this study, the penicillin resistance was related to the production of beta-lactamase, and the high minimal bactericidal concentration for cefoxitin was possibly associated with biofilm protection. Therefore, further studies are warranted to better understand biofilm formation, possibly contributing to our knowledge about bacterial resistance in vivo.
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