Trial reportPloS one2016
Performance of the Modified Mini-Mental State Examination (3MS) in Assessing Specific Cognitive Function in Patients Undergoing Peritoneal Dialysis.
Trial report in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.
- Prevalence of cognitive impairment among peritoneal dialysis patients: a systematic review and meta-analysis.Clinical and experimental nephrology · 2019Pooled it
- Article
- Anaemia as a Determinant of Cognitive Dysfunction in Peritoneal Dialysis Patients: Evidence from a Single-Centre Study.Medicina (Kaunas, Lithuania) · 2026Article
- The Diagnostic Performance of Screening Instruments for Mild Cognitive Impairment and Dementia in Chronic Kidney Disease and Kidney Failure: A Systematic Review and Meta-analysis.Kidney medicine · 2025Article
- Prediction model for cognitive impairment in maintenance hemodialysis patients: the role of diabetes.Frontiers in endocrinology · 2025Article
- Content Validity Assessment of the Revised Illness Perception Questionnaire in CKD Using Qualitative Methods.International journal of environmental research and public health · 2022Article
- Music Intervention Pilot Study: Assessing Teaching Methods of Group Marimba Classes Designed to Train Spatial Skills of Older Adults with Changes in Cognition.Music and medicine · 2021Article
- Cognitive and Motor Perseveration Are Associated in Older Adults.Frontiers in aging neuroscience · 2021Article
- The relationship between cognitive function and having diabetes in patients treated with hemodialysis.International journal of nursing sciences · 2020Article
- An association of cognitive impairment with diabetes and retinopathy in end stage renal disease patients under peritoneal dialysis.PloS one · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 6 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeWhile Cognitive impairment (CI) has been identified as an independent risk factors for mortality in patients undergoing peritoneal dialysis (PD), it is inadequately assessed. We evaluated the applicability of the Modified Mini-Mental State Examination (3MS) in assessing specific cognitive function and compared it to a detailed neuropsychological test battery as the reference standard.
methodsIn this multicentric cross-sectional study, we enrolled 445 clinically stable patients from five PD units, who were undergoing PD for at least 3 months. The 3MS was evaluated for general cognitive function. A detailed neuropsychological battery including domains of immediate memory, delayed memory, executive function, language, and visuospatial ability were evaluated as reference standards. Sensitivity and specificity of the 3MS was determined by using receiver operating characteristic (ROC) analysis.
resultsThe CI prevalence evaluated by 3MS was 23.6%. PD patients with CI performed worse in all cognitive domains. The 3MS correlated well with specific cognitive domains. However, 18.5%, 57.4%, 12.6%, 8.8%, and 41.2% of patients whom were idendified as normal by 3MS still showed executive dysfunction, immediate memory impairment, delayed memory impairment, and language-ability and visuospatial-ability impairment, respectively. The 3MS identified patients having specific cognitive dysfunction with varied extent of diagnostic value, with 0.50, 0.42, 0.35, 0.34, and 0.26 of Youden index in executive function, delayed memory, language ability, immediate memory, and visuospatial ability, respectively.
conclusionsThe 3MS is not a comprehensive instrument for major cognitive domains in PD patients. It could, however, be used for executive dysfunction and delayed memory impairment screening.
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