ArticleProceedings of the National Academy of Sciences of the United States of America2016
Cytoskeleton dynamics control the first asymmetric cell division in Arabidopsis zygote.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 78 papers.
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Who cites it
78 citing papers in PubMed, 174 citations in OpenAlex.
- Molecular understanding of plant pollination, fertilization, seed development and protoplast regeneration.Science China. Life sciences · 2026Review
- Interaction Between Actin and Microtubules During Plant Development.Cytoskeleton (Hoboken, N.J.) · 2026Review
- In Vitro Live Cell Imaging Reveals Nuclear Dynamics and Role of the Cytoskeleton During Asymmetric Division of Pollen Mitosis I in Nicotiana Benthamiana.Cytoskeleton (Hoboken, N.J.) · 2026Article
- Nuclear Entanglement: New Insights Into the Role of Cytoskeleton and Nucleoskeleton in Plant Nuclear Function.Cytoskeleton (Hoboken, N.J.) · 2026Review
- Temporal changes in surface tension guide microtubule organization and accurate asymmetric division of Arabidopsis zygotes.Nature communications · 2026Article
- Imaging and genetic toolbox to study Arabidopsis embryogenesis.The New phytologist · 2026Review
- KATANIN promotes cell elongation and division to generate proper cell numbers in maize organs.Nature communications · 2026Article
- KymoTip: high-throughput characterization of tip-growth dynamics in plant cells.The Plant journal : for cell and molecular biology · 2026Article
- Nuclear positioning and cell division site specification in plants.Journal of experimental botany · 2025Review
- A simple and versatile plasma membrane staining method for visualizing living cell morphology in reproductive tissues across diverse plant species.Plant methods · 2025Article
- Article
- Agent-based simulation of cortical microtubule band movement in arabidopsis zygotes.Scientific reports · 2025Article
- Distinct actin microfilament localization during early cell plate formation through deep learning-based image restoration.Plant cell reports · 2025Article
- Deep learning-based cytoskeleton segmentation for accurate high-throughput measurement of cytoskeleton density.Protoplasma · 2025Article
- Cytoplasmic inheritance: The transmission of plastid and mitochondrial genomes across cells and generations.Plant physiology · 2025Review
- Bioimaging insights into structural pathways of cell-to-cell communication within the male (MGU) and female (FGU) germ units of Arabidopsis thaliana.Plant cell reports · 2025Article
- How parental factors shape the plant embryo.Biochemical Society transactions · 2025Article
- Integration of basal and apical embryo lineage regulators controls F-actin cable integrity and zygote asymmetry inProceedings of the National Academy of Sciences of the United States of America · 2025Article
- The polar code for patterning: how polarity and the cytoskeleton orchestrate asymmetric cell division during plant development.Frontiers in cell and developmental biology · 2025Review
- Establishing cell polarity in plants: the role of cytoskeletal structures and regulatory pathways.Frontiers in cell and developmental biology · 2025Review
18 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
10 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The asymmetric cell division of the zygote is the initial and crucial developmental step in most multicellular organisms. In flowering plants, whether zygote polarity is inherited from the preexisting organization in the egg cell or reestablished after fertilization has remained elusive. How dynamically the intracellular organization is generated during zygote polarization is also unknown. Here, we used a live-cell imaging system with Arabidopsis zygotes to visualize the dynamics of the major elements of the cytoskeleton, microtubules (MTs), and actin filaments (F-actins), during the entire process of zygote polarization. By combining image analysis and pharmacological experiments using specific inhibitors of the cytoskeleton, we found features related to zygote polarization. The preexisting alignment of MTs and F-actin in the egg cell is lost on fertilization. Then, MTs organize into a transverse ring defining the zygote subapical region and driving cell outgrowth in the apical direction. F-actin forms an apical cap and longitudinal arrays and is required to position the nucleus to the apical region of the zygote, setting the plane of the first asymmetrical division. Our findings show that, in flowering plants, the preexisting cytoskeletal patterns in the egg cell are lost on fertilization and that the zygote reorients the cytoskeletons to perform directional cell elongation and polar nuclear migration.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.