Evidence map›Paper›PMID 27911435›Full record

ArticlePediatric research2017

Detecting biomarkers of secondhand marijuana smoke in young children.

Karen M Wilson, Michelle R Torok, Binnian Wei, Lanqing Wang, Michelle Robinson, Connie S Sosnoff, Benjamin C Blount

Open access · bronzeAbstract read
In one paragraph

Article in Pediatric research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
4.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 38 citations in OpenAlex.

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  10. Management of Cannabis Use in Breastfeeding Women: The Untapped Potential of International Board Certified Lactation Consultants.Breastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine · 2020
    Article
  11. Article
  12. Article
  13. Indoor cannabis smoke and children's health.Preventive medicine reports · 2019
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Karen M WilsonDepartment of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, New York.
Michelle R TorokAmerican Academy of Pediatrics Julius B. Richmond Center of Excellence, Elk Grove Village, Illinois.
Binnian WeiTobacco and Volatiles Branch, Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, Georgia.
Lanqing WangTobacco and Volatiles Branch, Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, Georgia.
Michelle RobinsonPediatric Hospital Medicine, Children's Hospital, Aurora, Colorado.
Connie S SosnoffTobacco and Volatiles Branch, Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, Georgia.
Benjamin C BlountTobacco and Volatiles Branch, Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, Georgia.
Centers for Disease Control and Prevention · USAmerican Academy of Pediatrics · USUniversity of Colorado Denver · US

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

backgroundThe impact of secondhand marijuana smoke exposure on children is unknown. New methods allow detection of secondhand marijuana smoke in children.

methodsWe studied children ages 1 mo to 2 y hospitalized with bronchiolitis in Colorado from 2013 to 2015. Parents completed a survey, and urine samples were analyzed for cotinine using LC/MS/MS (limits of detection 0.03 ng/ml) and marijuana metabolites including COOH-THC (limits of detection 0.015 ng/ml).

resultsA total of 43 subjects had urine samples available for analysis. Most (77%) of the subjects were male, and 52% were less than 1 y of age. COOH-THC was detectable in 16% of the samples analyzed (THC+); the range in COOH-THC concentration was 0.03-1.5 ng/ml. Two subjects had levels >1 ng/ml. Exposure did not differ by gender or age. Non-white children had more exposure than white children (44 vs. 9%; P < 0.05). 56% of children with cotinine >2.0 ng/ml were THC+, compared with 7% of those with lower cotinine (P < 0.01).

conclusionMetabolites of marijuana smoke can be detected in children; in this cohort, 16% were exposed. Detectable COOH-THC is more common in children with tobacco smoke exposure. More research is needed to assess the health impacts of marijuana smoke exposure on children and inform public health policy.

Indexed as

BiomarkersChild, PreschoolCohort StudiesColoradoCotinineDronabinolFemaleHospitalizationHumansInfantLimit of DetectionMaleMarijuana SmokingParentsSex FactorsSmokeBiomarkersCotinineDronabinolSmoke

Identifiers

PMID27911435
PMCPMC5701510
OpenAlexW2558549372

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.