Trial reportDiagnostic and interventional radiology (Ankara, Turkey)
Contrast-enhanced US-guided percutaneous biopsy of anterior mediastinal lesions.
Trial report in Diagnostic and interventional radiology (Ankara, Turkey). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Efficacy of CEUS-guided biopsy for thoracic and pulmonary lesions: a systematic review and meta-analysis.BMC medical imaging · 2025Pooled it
- Contrast-Enhanced Ultrasound Improves the Pathological Outcomes of US-Guided Core Needle Biopsy That Targets the Viable Area of Anterior Mediastinal Masses.BioMed research international · 2018Trial
- Biopsy Needle Integrated with Rotational Oblique Spectral Ultrasound (ROSUS) Imaging.Sensors (Basel, Switzerland) · 2026Article
- Impacting factors of diagnostic accuracy of ultrasound-guided percutaneous core needle biopsy in mediastinal lesions: an analysis with 622 cases.Journal of thoracic disease · 2025Article
- An Innovative Management in the Diagnosis of Mediastinal Masses.Thoracic cancer · 2025Observational
- Minimally Invasive Sampling of Mediastinal Lesions.Life (Basel, Switzerland) · 2024Review
- Imaging performance of thoracic SMARCA4-deficient undifferentiated tumor: a case report and literature review.Translational lung cancer research · 2024Article
- Efficacy of contrast-enhanced ultrasound-guided percutaneous core needle biopsy in anterior mediastinal masses.Journal of interventional medicine · 2022Article
- Marked safety and high diagnostic yield of freehand ultrasound-guided core-needle biopsies performed by pulmonologists.Thoracic cancer · 2022Article
- Safety and Efficacy of Percutaneous Image-Guided Mediastinal Mass Core-Needle Biopsy.Mayo Clinic proceedings. Innovations, quality & outcomes · 2021Article
- Contrast-enhanced ultrasound for needle biopsy of thoracic lesions.Oncology letters · 2020Article
- Clinical value of contrast-enhanced ultrasound in transthoracic biopsy of malignant anterior mediastinal masses.Journal of thoracic disease · 2019Article
- Chinese multidisciplinary expert consensus: Guidelines on percutaneous transthoracic needle biopsy.Thoracic cancer · 2018Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeWe aimed to explore the value of contrast-enhanced ultrasonography (CEUS) in guidance of percutaneous biopsy of anterior mediastinal lesions.
methodsNinety patients with solitary anterior mediastinal lesions (55 males, 35 females; mean age, 46±4 years) were included. Patients were randomly divided into CEUS group (n=45) and conventional ultrasonography (US) group (n=45). Real-time US-guided core needle (16 G) percutaneous biopsies were performed in all lesions. The display of internal mammary arteries, internal necrosis, and active areas were recorded and compared. Biopsy success rate and diagnostic accuracy were compared between the two groups.
resultsDisplay rate of unenhanced internal necrosis was higher in the CEUS group than in the US group (88.9% vs. 46.7%, P = 0.041). With real-time CEUS guidance, internal mammary arteries were effectively displayed and avoided during biopsies in 68.9% of the lesions (31/45). Of the lesions, 88.9% (80/90) were histologically proven, including 13 benign lesions and 67 malignancies. There was a significant difference in the rate of successful puncture attempts between the two groups (P = 0.041). CEUS group had a higher biopsy success rate (100% vs. 95.5%, P = 0.045) and higher diagnostic accuracy (97.8% vs. 82.2%, P = 0.035) compared with the US group (P = 0.035).
conclusionCEUS guidance is a promising technique in depicting internal necrotic areas, viable areas, and internal mammary arteries during percutaneous biopsy of anterior mediastinal lesion, with satisfying safety, accuracy, and success rates.
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