Evidence map›Paper›PMID 27911025›Full record

ArticleArtificial organs2016

Effect of Balloon-Expandable Transcatheter Aortic Valve Replacement Positioning: A Patient-Specific Numerical Model.

Matteo Bianchi, Gil Marom, Ram P Ghosh, Harold A Fernandez, James R Taylor, Marvin J Slepian, Danny Bluestein

Open access · greenAbstract read
In one paragraph

Article in Artificial organs, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it, 55 citations in OpenAlex.

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  16. Biomechanics of Transcatheter Aortic Valve Implant.Bioengineering (Basel, Switzerland) · 2022
    Review
  17. Article
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Matteo BianchiDepartment of Biomedical Engineering.
Gil MaromDepartment of Biomedical Engineering.
Ram P GhoshDepartment of Biomedical Engineering.
Harold A FernandezDepartment of Surgery, Division of Cardiothoracic Surgery, Stony Brook University Hospital, Stony Brook, NY.
James R TaylorDepartment of Surgery, Division of Cardiothoracic Surgery, Stony Brook University Hospital, Stony Brook, NY.
Marvin J SlepianDepartment of Biomedical Engineering.
Danny BluesteinDepartment of Biomedical Engineering.
Stony Brook University Hospital · USUniversity of Arizona · US

Funding

Optimizing Cardiovascular Device Thromboresistance for Eliminating AnticoagulantsU01EB012487 · NIBIB · STATE UNIVERSITY NEW YORK STONY BROOK · PI BLUESTEIN, DANNY · 2010 to 2014
$6.9M
NIBIB NIH HHS U01 EB012487
6 · The paper itself

Abstract

Transcatheter aortic valve replacement (TAVR) has emerged as a life-saving and effective alternative to surgical valve replacement in high-risk, elderly patients with severe calcific aortic stenosis. Despite its early promise, certain limitations and adverse events, such as suboptimal placement and valve migration, have been reported. In the present study, it was aimed to evaluate the effect of various TAVR deployment locations on the procedural outcome by assessing the risk for valve migration. The deployment of a balloon-expandable Edwards SAPIEN valve was simulated via finite element analysis in a patient-specific calcified aortic root, which was reconstructed from CT scans of a retrospective case of valve migration. The deployment location was parametrized in three configurations and the anchorage was quantitatively assessed based on the contact between the stent and the native valve during the deployment and recoil phases. The proximal deployment led to lower contact area between the native leaflets and the stent which poses higher risk for valve migration. The distal and midway positions resulted in comparable outcomes, with the former providing a slightly better anchorage. The approach presented might be used as a predictive tool for procedural planning in order to prevent prosthesis migration and achieve better clinical outcomes.

Indexed as

Prosthesis FailureAged, 80 and overAortaAortic ValveAortic Valve StenosisCalcinosisComputer SimulationFinite Element AnalysisHumansMaleModels, AnatomicModels, BiologicalProsthesis DesignRetrospective StudiesTranscatheter Aortic Valve ReplacementTreatment OutcomeAortic stenosisCalcificationCrimpingFinite element analysisTranscatheter aortic valve replacement

Identifiers

PMID27911025
PMCPMC5137806
OpenAlexW2559754345

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.