Evidence map›Paper›PMID 27910257›Full record

ArticlePain practice : the official journal of World Institute of Pain2017

Neurostimulation for Postsurgical Analgesia: A Novel System Enabling Ultrasound-Guided Percutaneous Peripheral Nerve Stimulation.

Brian M Ilfeld, Stuart A Grant, Christopher A Gilmore, John Chae, Richard D Wilson, Amorn Wongsarnpigoon, Joseph W Boggs

Open access · hybridAbstract read
In one paragraph

Article in Pain practice : the official journal of World Institute of Pain, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 3 pooled it
8.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 3 syntheses or guidelines pooled it, 83 citations in OpenAlex.

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  18. Peripheral Nervous System Pain Modulation.Current neuropharmacology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Brian M IlfeldDepartment of Anesthesiology, University of California San Diego, San Diego, California, U.S.A.
Stuart A GrantDepartment of Anesthesiology, Duke University Medical Center, Durham, North Carolina, U.S.A.
Christopher A GilmoreDepartment of Anesthesiology, Wake Forest University Baptist Medical Center, Winston-Salem, North Carolina, U.S.A.
John ChaeDepartment of Physical Medicine and Rehabilitation, Case Western Reserve University, Cleveland, Ohio, U.S.A.
Richard D WilsonDepartment of Physical Medicine and Rehabilitation, Case Western Reserve University, Cleveland, Ohio, U.S.A.
Amorn WongsarnpigoonSPR Therapeutics, Chapel Hill, North Carolina, U.S.A.
Joseph W BoggsSPR Therapeutics, Chapel Hill, North Carolina, U.S.A.
MetroHealth · USSprint PNS System (United States) · USAtrium Health Wake Forest Baptist · USDuke University Hospital · USUniversity of California, San Diego · US

Funding

Electrical stimulation to reduce pain and improve function after knee replacementR44AG052196 · NIA · SPR THERAPEUTICS, LLC · PI BOGGS, JOSEPH WILDER · 2015 to 2023
$4.9M
NIA NIH HHS R44 AG052196
6 · The paper itself

Abstract

While neurostimulation-stimulation of the nervous system using electrical current-has been used to treat chronic pain, its use treating postsurgical pain has been limited. Here, we report on the clinical application of a novel investigational lead to provide analgesia following total knee arthroplasty. In 5 subjects, leads were inserted percutaneously using ultrasound guidance within 0.5 to 3.0 cm of the femoral and/or sciatic nerve(s). With the delivery of current, pain decreased an average of 63% at rest, with 4 of 5 subjects having relief of > 50%. During passive and active knee flexion, pain decreased an average of 14% and 50%, with 0/3 and 1/2 subjects attaining > 50% relief, respectively. Ultrasound-guided percutaneous peripheral nerve stimulation may be a practical modality for the treatment of postsurgical pain.

Indexed as

Proof of Concept StudyAdultAnalgesiaArthroplasty, Replacement, KneeFemaleHumansMaleMiddle AgedPain ManagementPain MeasurementPostoperative PainTranscutaneous Electric Nerve StimulationUltrasonography, Interventionalhelical leadneuromodulationpercutaneous peripheral nerve stimulationperipheral nerve stimulatorpostoperative painsmall-diameter open-coiled helical lead

Identifiers

PMID27910257
PMCPMC5637916
OpenAlexW2557783154

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.