ArticleAutism research : official journal of the International Society for Autism Research2017
Auditory processing in noise is associated with complex patterns of disrupted functional connectivity in autism spectrum disorder.
Article in Autism research : official journal of the International Society for Autism Research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 3 of them syntheses that pooled it.
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Who cites it
35 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Auditory Sensitivity in Autism: A Systematic Review of Mismatch Negativity and Mismatch Field Responses.Autism research : official journal of the International Society for Autism Research · 2026Pooled it
- Autism Spectrum Disorder and auditory sensory alterations: a systematic review on the integrity of cognitive and neuronal functions related to auditory processing.Journal of neural transmission (Vienna, Austria : 1996) · 2023Pooled it
- Functional Brain Connectivity of Language Functions in Children Revealed by EEG and MEG: A Systematic Review.Frontiers in human neuroscience · 2020Pooled it
- Linking auditory brain responses to cortical microstructure and sensory behaviors in autism spectrum disorder: a preliminary study.Frontiers in psychiatry · 2026Article
- Lower Cortical Activation and Altered Functional Connectivity Characterize Passive Auditory Spatial Attention in ASD.Autism research : official journal of the International Society for Autism Research · 2025Article
- Auditory and Semantic Processing of Speech-in-Noise in Autism: A Behavioral and EEG Study.Autism research : official journal of the International Society for Autism Research · 2025Article
- Lower cortical activation and altered functional connectivity characterize passive auditory spatial attention in ASD.bioRxiv : the preprint server for biology · 2025Article
- Characterizing Directional Dynamics of Semantic Prediction Based on Inter-regional Temporal Generalization.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- How auditory processing influences the autistic profile: A review.Autism research : official journal of the International Society for Autism Research · 2024Review
- Incidence of Otolaryngological Manifestations in Individuals with Autism Spectrum Disorder: A Special Focus on Auditory Disorders.Audiology research · 2024Review
- Speech Reception in Young Children with Autism Is Selectively Indexed by a Neural Oscillation Coupling Anomaly.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Decreased thalamocortical connectivity in resolved Rolandic epilepsy.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2023Article
- TheFrontiers in behavioral neuroscience · 2023Article
- Auditory Brainstem Response in Autistic Children: Implications for Sensory Processing.Hearing, balance and communication · 2023Article
- Cortical signatures of auditory object binding in children with autism spectrum disorder are anomalous in concordance with behavior and diagnosis.PLoS biology · 2022Article
- Too Blind to See the Elephant? Why Neuroscientists Ought to Be Interested in Tinnitus.Journal of the Association for Research in Otolaryngology : JARO · 2021Review
- Children with autism spectrum disorder show altered functional connectivity and abnormal maturation trajectories in response to inverted faces.Autism research : official journal of the International Society for Autism Research · 2021Article
- Aberrant auditory system and its developmental implications for autism.Science China. Life sciences · 2021Review
- Auditory Discrimination in Autism Spectrum Disorder.Frontiers in neuroscience · 2021Review
- Classification of evoked responses to inverted faces reveals both spatial and temporal cortical response abnormalities in Autism spectrum disorder.NeuroImage. Clinical · 2021Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
Autism spectrum disorder (ASD) is associated with difficulty in processing speech in a noisy background, but the neural mechanisms that underlie this deficit have not been mapped. To address this question, we used magnetoencephalography to compare the cortical responses between ASD and typically developing (TD) individuals to a passive mismatch paradigm. We repeated the paradigm twice, once in a quiet background, and once in the presence of background noise. We focused on both the evoked mismatch field (MMF) response in temporal and frontal cortical locations, and functional connectivity with spectral specificity between those locations. In the quiet condition, we found common neural sources of the MMF response in both groups, in the right temporal gyrus and inferior frontal gyrus (IFG). In the noise condition, the MMF response in the right IFG was preserved in the TD group, but reduced relative to the quiet condition in ASD group. The MMF response in the right IFG also correlated with severity of ASD. Moreover, in noise, we found significantly reduced normalized coherence (deviant normalized by standard) in ASD relative to TD, in the beta band (14-25 Hz), between left temporal and left inferior frontal sub-regions. However, unnormalized coherence (coherence during deviant or standard) was significantly increased in ASD relative to TD, in multiple frequency bands. Our findings suggest increased recruitment of neural resources in ASD irrespective of the task difficulty, alongside a reduction in top-down modulations, usually mediated by the beta band, needed to mitigate the impact of noise on auditory processing. Autism Res 2016,. © 2016 International Society for Autism Research, Wiley Periodicals, Inc. Autism Res 2017, 10: 631-647. © 2016 International Society for Autism Research, Wiley Periodicals, Inc.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.