Evidence map›Paper›PMID 27909920›Full record

ReviewJournal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry2017

Beyond ferryl-mediated hydroxylation: 40 years of the rebound mechanism and C-H activation.

Xiongyi Huang, John T Groves

Abstract readReview
In one paragraph

Review in Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 118 papers.

0numbers the graph read from it
0cells of the map it votes in
118citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

118 citing papers in PubMed.

  1. Article
  2. Article
  3. Exploring the structural, morphological and optical properties of iron based metalloporphyrin in the nano regime for biomedical applications.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Total Synthesis of (+)-12-The Journal of organic chemistry · 2026
    Article
  8. Review
  9. Article
  10. Review
  11. The Effect ofACS medicinal chemistry letters · 2026
    Article
  12. Review
  13. Article
  14. Manipulating Terminal Iron-Hydroxide Nucleophilicity through Redox.Journal of the American Chemical Society · 2026
    Article
  15. Review
  16. Article
  17. Bimolecular Homolytic Substitution (SACS central science · 2025
    Review
  18. Article
  19. Light-Promoted C(spJournal of the American Chemical Society · 2025
    Article
  20. Article

58 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Xiongyi HuangPrinceton University, Princeton, USA.
John T GrovesPrinceton University, Princeton, USA. jtgroves@princeton.edu.

Funding

Molecular Probes of the Mechanisms of Cytocrhome P450R37GM036298 · NIGMS · PRINCETON UNIVERSITY · PI GROVES, JOHN TAYLOR · 2007 to 2016
$3.7M
NIGMS NIH HHS R37 GM036298
6 · The paper itself

Abstract

Since our initial report in 1976, the oxygen rebound mechanism has become the consensus mechanistic feature for an expanding variety of enzymatic C-H functionalization reactions and small molecule biomimetic catalysts. For both the biotransformations and models, an initial hydrogen atom abstraction from the substrate (R-H) by high-valent iron-oxo species (Fe

Indexed as

BiotransformationCarbonFerric CompoundsHydrogenHydroxylationOxygenasesCarbonFerric Compoundsferric hydroxideHydrogenOxygenasesC–H activationIronMetal oxoOxygenaseRadicalRebound

Identifiers

PMID27909920
PMCPMC5350257

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.