ArticleTurkish journal of anaesthesiology and reanimation2016
Effect of Day and Night Desflurane Anaesthesia on Melatonin Levels in Rats.
Article in Turkish journal of anaesthesiology and reanimation, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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6 authors at 1 institution in 1 country.
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Abstract
objectiveThe aim of this study is to investigate the effect of day and night administration of desflurane anaesthesia on melatonin levels in rats.
methodsTwenty-four 15-day-old rats were included in the study and were divided into four groups. The rats were anaesthetised between 19:00-01:00 (night group) and 07:00-13:00 (day group) with 5.7% desflurane concentration in 6 L min
resultsThere was a statistically significant difference between the groups (p=0.007). Between group day control and group night control there was a statistically significant difference (p=0.042). Further, there was a significant difference between group day control and night desfluran as well (p=0.024). We could not find any difference between other groups.
conclusionThis study showed that 6 hours of 5.7% desflurane anaesthesia during day and night hours did not significantly change melatonin levels.
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