ReviewCancer nanotechnology2016
Synthetic nanoparticles for delivery of radioisotopes and radiosensitizers in cancer therapy.
Review in Cancer nanotechnology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 56 citations in OpenAlex.
- Assembling a new generation of radiopharmaceuticals with supramolecular theranostics.Nature reviews. Chemistry · 2024Review
- Quantitative Single-Cell Comparison of Sensitization to Radiation and a Radiomimetic Drug for Diverse Gold Nanoparticle Coatings.Small science · 2024Article
- Revolutionizing head and neck squamous cell carcinoma treatment with nanomedicine in the era of immunotherapy.Frontiers in immunology · 2024Review
- Evaluation of Therapeutic Efficacy and Imaging Capabilities ofPharmaceutics · 2023Article
- Unleashing novel horizons in advanced prostate cancer treatment: investigating the potential of prostate specific membrane antigen-targeted nanomedicine-based combination therapy.Frontiers in immunology · 2023Review
- Application of nanomedicine in radiotherapy sensitization.Frontiers in oncology · 2023Review
- Article
- Hydroxyapatite Nanoparticles for Improved Cancer Theranostics.Journal of functional biomaterials · 2022Review
- Matrices and Affinity Ligands for Antibody Purification and Corresponding Applications in Radiotherapy.Biomolecules · 2022Review
- Radiolabeled nanomaterials for biomedical applications: radiopharmacy in the era of nanotechnology.EJNMMI radiopharmacy and chemistry · 2022Review
- Advanced diagnostic and therapeutic strategies in nanotechnology for lung cancer.Frontiers in oncology · 2022Review
- Advances of Nanomedicine in Radiotherapy.Pharmaceutics · 2021Review
- Microspheres Used in Liver Radioembolization: From Conception to Clinical Effects.Molecules (Basel, Switzerland) · 2021Review
- Remotely Activated Nanoparticles for Anticancer Therapy.Nano-micro letters · 2020Review
- Trastuzumab Conjugated Superparamagnetic Iron Oxide Nanoparticles Labeled withMolecules (Basel, Switzerland) · 2020Article
- Chemical Mechanisms of Nanoparticle Radiosensitization and Radioprotection: A Review of Structure-Function Relationships Influencing Reactive Oxygen Species.International journal of molecular sciences · 2020Review
- Iron oxide nanoparticulate system as a cornerstone in the effective delivery of Tc-99 m radionuclide: a potential molecular imaging probe for tumor diagnosis.Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences · 2019Article
- Harnessing Microglia and Macrophages for the Treatment of Glioblastoma.Frontiers in pharmacology · 2019Review
- Metal-basedTheranostics · 2018Review
- Effect of gold nanoparticles on radiation doses in tumor treatment: a Monte Carlo study.Lasers in medical science · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Radiotherapy has been, and will continue to be, a critical modality to treat cancer. Since the discovery of radiation-induced cytotoxicity in the late 19th century, both external and internal radiation sources have provided tremendous benefits to extend the life of cancer patients. Despite the dramatic improvement of radiation techniques, however, one challenge persists to limit the anti-tumor efficacy of radiotherapy, which is to maximize the deposited dose in tumor while sparing the rest of the healthy vital organs. Nanomedicine has stepped into the spotlight of cancer diagnosis and therapy during the past decades. Nanoparticles can potentiate radiotherapy by specifically delivering radionuclides or radiosensitizers into tumors, therefore enhancing the efficacy while alleviating the toxicity of radiotherapy. This paper reviews recent advances in synthetic nanoparticles for radiotherapy and radiosensitization, with a focus on the enhancement of in vivo anti-tumor activities. We also provide a brief discussion on radiation-associated toxicities as this is an area that, up to date, has been largely missing in the literature and should be closely examined in future studies involving nanoparticle-mediated radiosensitization.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.