Evidence map›Paper›PMID 27909264›Full record

ArticleJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2017

Global ablation of the mitochondrial calcium uniporter increases glycolysis in cortical neurons subjected to energetic stressors.

Matthew Nichols, Pia A Elustondo, Jordan Warford, Aruloli Thirumaran, Evgeny V Pavlov, George S Robertson

Open access · bronzeAbstract read
In one paragraph

Article in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 49 citations in OpenAlex.

  1. Article
  2. Article
  3. Mitochondrial CaBiomolecules · 2026
    Review
  4. Mitochondrial CaCell calcium · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. The mitochondrial CabioRxiv : the preprint server for biology · 2023
    Article
  12. Review
  13. The mitochondrial CaFrontiers in cell and developmental biology · 2023
    Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Neuron-Oligodendrocyte Interactions in the Structure and Integrity of Axons.Frontiers in cell and developmental biology · 2021
    Review
  19. The mitochondrial calcium uniporter is crucial for the generation of fast cortical network rhythms.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2020
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Matthew Nichols1 Faculty of Medicine, Department of Pharmacology, Brain Repair Centre, Life Sciences Research Institute, Dalhousie University, Halifax, Canada.
Pia A Elustondo2 Faculty of Medicine, Department of Physiology and Biophysics, Dalhousie University, Halifax, Canada.
Jordan Warford3 Faculty of Medicine, Department of Pathology, Dalhousie University, Halifax, Canada.
Aruloli Thirumaran1 Faculty of Medicine, Department of Pharmacology, Brain Repair Centre, Life Sciences Research Institute, Dalhousie University, Halifax, Canada.
Evgeny V Pavlov4 Department of Basic Sciences, College of Dentistry, New York University, New York, NY, USA.
George S Robertson1 Faculty of Medicine, Department of Pharmacology, Brain Repair Centre, Life Sciences Research Institute, Dalhousie University, Halifax, Canada.
Dalhousie University · CANew York University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The effects of global mitochondrial calcium (Ca

Indexed as

Energy MetabolismGlycolysisAnimalsBrainCalciumCalcium ChannelsCells, CulturedCell SurvivalFemaleHypoxia-Ischemia, BrainIschemic PreconditioningMaleMice, KnockoutMicroscopy, Electron, TransmissionMitochondriaMitochondrial Membrane Transport ProteinsCalciumCalcium Channelsmitochondrial calcium uniporterMitochondrial Membrane Transport ProteinsMitochondrial Permeability Transition PoreGlycolysishypoxic preconditioningmitochondrial calcium uniporterneuronal bioenergeticsstroke

Identifiers

PMID27909264
PMCPMC5536808
OpenAlexW2557537936

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.