Evidence map›Paper›PMID 27909228›Full record

ArticleJournal of applied physiology (Bethesda, Md. : 1985)2017

Divergent outcomes of fructose consumption on exercise capacity of rats: friend or foe.

Angela Sun, An Huang, Elizabeth Kertowidjojo, Su Song, Thomas H Hintze, Dong Sun

Open access · bronzeAbstract read
In one paragraph

Article in Journal of applied physiology (Bethesda, Md. : 1985), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Angela SunDepartment of Physiology, New York Medical College, Valhalla, New York.
An HuangDepartment of Physiology, New York Medical College, Valhalla, New York.
Elizabeth KertowidjojoDepartment of Physiology, New York Medical College, Valhalla, New York.
Su SongDepartment of Physiology, New York Medical College, Valhalla, New York.
Thomas H HintzeDepartment of Physiology, New York Medical College, Valhalla, New York.
Dong SunDepartment of Physiology, New York Medical College, Valhalla, New York dong_sun@nymc.edu.
New York Medical College · US

Funding

Estrogen and EDHF in NO DeficiencyR01HL070653 · NHLBI · NEW YORK MEDICAL COLLEGE · PI HUANG, AN · 2003 to 2017
$3.7M
Ferrochelatase & guanylate cyclase regulation in vascular dysfunctionR01HL129797 · NHLBI · NEW YORK MEDICAL COLLEGE · PI SUN, DONG, WOLIN, MICHAEL S · 2016 to 2019
$1.6M
NHLBI NIH HHS R01 HL070653NHLBI NIH HHS R01 HL129797
6 · The paper itself

Abstract

To test the hypothesis that high fructose (HF) consumption divergently affects exercise capability as a function of feeding duration, rats were fed a normal (as control) diet or a normal caloric diet with HF for 3, 6, 10, and 30 days, respectively, and then were run on a treadmill. Results show that running distance and work were significantly increased, which was associated with greater exercise oxygen consumption in rats fed HF for 3 (HF-3D) and 6 days, but were decreased in rats fed HF for 30 days (HF-30D) compared with rats in their respective control groups. Shear stress-induced vasodilation (SSID) in isolated plantaris muscle arterioles was significantly greater in the HF-3D group than the control group. The difference in SSID between the two groups was abolished by

Indexed as

AnimalsArteriolesEndothelium, VascularFructoseMuscle, SkeletalNG-Nitroarginine Methyl EsterNitric OxideNitric Oxide SynthaseNitric Oxide Synthase Type IIIOxidative StressOxygen ConsumptionPhysical Conditioning, AnimalRatsShear StrengthSuperoxidesVasodilationFructoseNG-Nitroarginine Methyl EsterNitric OxideNitric Oxide SynthaseNitric Oxide Synthase Type IIISuperoxidesVasodilator Agentsexercisefructosenitric oxideoxygen consumptionshear stress-induced vasodilation

Identifiers

PMID27909228
PMCPMC5338603
OpenAlexW2558868040

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.