Evidence map›Paper›PMID 27909071›Full record

Trial reportNeurorehabilitation and neural repair2017

Does Task-Specific Training Improve Upper Limb Performance in Daily Life Poststroke?

Kimberly J Waddell, Michael J Strube, Ryan R Bailey, Joseph W Klaesner, Rebecca L Birkenmeier, Alexander W Dromerick, Catherine E Lang

Registry-linked trialOpen access · bronzeAbstract readClinical Trial, Phase IIRandomized Controlled Trial
In one paragraph

Trial report in Neurorehabilitation and neural repair, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05248178 (Pilot Testing of tDCS and Metacognitive Strategy Training in Chronic Stroke), which is not on this map. Cited by 94 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
94citing papers in PubMed, 1 pooled it
12.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05248178 naterminatednot on this mapstarted 2022, after this paper: background citation

Pilot Testing of tDCS and Metacognitive Strategy Training in Chronic Stroke

TypeinterventionalSponsorUniversity of Missouri-ColumbiaRan2022 to 2025Enrolled11ConditionsChronic StrokeArmsCO-OP Procedures, tDCS, Computer Cognitive Training Procedures, sham tDCS group
3 · Its place in the literature

Who cites it

94 citing papers in PubMed, 1 synthesis or guideline pooled it, 169 citations in OpenAlex.

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34 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Kimberly J Waddell1 Washington University, St Louis, MO, USA.
Michael J Strube1 Washington University, St Louis, MO, USA.
Ryan R Bailey1 Washington University, St Louis, MO, USA.
Joseph W Klaesner1 Washington University, St Louis, MO, USA.
Rebecca L Birkenmeier1 Washington University, St Louis, MO, USA.
Alexander W Dromerick2 Georgetown University, Washington, DC, USA.
Catherine E Lang1 Washington University, St Louis, MO, USA.
Washington University in St. Louis · USGeorgetown University · US

Funding

Washington University Institute of Clinical and Translational SciencesKL2TR000450 · NCATS · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2012 to 2016
$8.8M
Translation of in-clinic Gains to Gains in Daily Life After StrokeR01HD068290 · NICHD · WASHINGTON UNIVERSITY · PI LANG, CATHERINE · 2012 to 2021
$4.0M
Translation of In-Clinic Gains to Gains in Daily LifeR37HD068290 · NICHD · WASHINGTON UNIVERSITY · PI Catherine Lang · 2022 to 2026
$2.7M
Washington University Institute of Clinical and Translational SciencesTL1TR000449 · NCATS · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2012 to 2016
$2.5M
NCATS NIH HHS KL2 TR000450NCATS NIH HHS TL1 TR000449NICHD NIH HHS R01 HD068290NICHD NIH HHS R37 HD068290
6 · The paper itself

Abstract

backgroundA common assumption is that changes in upper limb (UL) capacity, or what an individual is capable of doing, translates to improved UL performance in daily life, or what an individual actually does. This assumption should be explicitly tested for individuals with UL paresis poststroke.

objectiveTo examine changes in UL performance after an intensive, individualized, progressive, task-specific UL intervention for individuals at least 6 months poststroke.

methodsSecondary analysis on 78 individuals with UL paresis who participated in a phase II, single-blind, randomized parallel dose-response trial. Participants were enrolled in a task-specific intervention for 8 weeks. Participants were randomized into 1 of 4 treatment groups with each group completing different amounts of UL movement practice. UL performance was assessed with bilateral, wrist-worn accelerometers once a week for 24 hours throughout the duration of the study. The 6 accelerometer variables were tested for change and the influence of potential modifiers using hierarchical linear modeling.

resultsNo changes in UL performance were found on any of the 6 accelerometer variables used to quantify UL performance. Neither changes in UL capacity nor the overall amount of movement practice influenced changes in UL performance. Stroke chronicity, baseline UL capacity, concordance, and ADL status significantly increased the baseline starting points but did not influence the rate of change (slopes) for participants.

conclusionsImproved motor capacity resulting from an intensive outpatient UL intervention does not appear to translate to increased UL performance outside the clinic.

Indexed as

Activities of Daily LivingExercise TherapyStroke RehabilitationAccelerometryFemaleHumansLinear ModelsMaleMiddle AgedParesisSingle-Blind MethodStrokeTreatment OutcomeUpper Extremityaccelerometrystroketask-specific trainingupper limb

Identifiers

PMID27909071
PMCPMC5481638
OpenAlexW2558804171

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.