ArticleNeuroImage2017
Fractionating the anterior temporal lobe: MVPA reveals differential responses to input and conceptual modality.
Article in NeuroImage, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed.
- Default mode network can support the level of detail in experience during active task states.Proceedings of the National Academy of Sciences of the United States of America · 2018Trial
- Transcranial focused ultrasound stimulation enhances semantic memory by modulating brain morphology, neurochemistry and neural dynamics.Nature communications · 2026Article
- Article
- Mapping Contributions of the Anterior Temporal Semantic Hub to the Processing of Abstract and Concrete Verbs.Human brain mapping · 2025Article
- How does the "default mode" network contribute to semantic cognition?Brain and language · 2024Review
- Diffusion magnetic resonance imaging connectome features are predictive of functional lateralization of semantic processing in the anterior temporal lobes.Human brain mapping · 2023Article
- Temporopolar regions of the human brain.Brain : a journal of neurology · 2023Article
- Context free and context-dependent conceptual representation in the brain.Cerebral cortex (New York, N.Y. : 1991) · 2022Article
- Flexing the principal gradient of the cerebral cortex to suit changing semantic task demands.eLife · 2022Article
- Temporal pole volume is associated with episodic autobiographical memory in healthy older adults.Hippocampus · 2022Article
- Electrocorticographic evidence of a common neurocognitive sequence for mentalizing about the self and others.Nature communications · 2022Article
- Article
- Knowing what you need to know in advance: The neural processes underpinning flexible semantic retrieval of thematic and taxonomic relations.NeuroImage · 2021Article
- Dynamic activity patterns in the anterior temporal lobe represents object semantics.Cognitive neuroscience · 2020Article
- The Neural Mechanism of the Social Framing Effect: Evidence from fMRI and tDCS Studies.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020Article
- Distinct individual differences in default mode network connectivity relate to off-task thought and text memory during reading.Scientific reports · 2019Article
- Dissociations in semantic cognition: Oscillatory evidence for opposing effects of semantic control and type of semantic relation in anterior and posterior temporal cortex.Cortex; a journal devoted to the study of the nervous system and behavior · 2019Article
- The effects of psychiatric history and age on self-regulation of the default mode network.NeuroImage · 2019Article
- Composing lexical versus functional adjectives: Evidence for uniformity in the left temporal lobe.Psychonomic bulletin & review · 2018Article
- Integrated deep visual and semantic attractor neural networks predict fMRI pattern-information along the ventral object processing pathway.Scientific reports · 2018Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Words activate cortical regions in accordance with their modality of presentation (i.e., written vs. spoken), yet there is a long-standing debate about whether patterns of activity in any specific brain region capture modality-invariant conceptual information. Deficits in patients with semantic dementia highlight the anterior temporal lobe (ATL) as an amodal store of semantic knowledge but these studies do not permit precise localisation of this function. The current investigation used multiple imaging methods in healthy participants to examine functional dissociations within ATL. Multi-voxel pattern analysis identified spatially segregated regions: a response to input modality in anterior superior temporal gyrus (aSTG) and a response to meaning in more ventral anterior temporal lobe (vATL). This functional dissociation was supported by resting-state connectivity that found greater coupling for aSTG with primary auditory cortex and vATL with the default mode network. A meta-analytic decoding of these connectivity patterns implicated aSTG in processes closely tied to auditory processing (such as phonology and language) and vATL in meaning-based tasks (such as comprehension or social cognition). Thus we provide converging evidence for the segregation of meaning and input modality in the ATL.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.