Evidence map›Paper›PMID 27908464›Full record

Trial reportBurns : journal of the International Society for Burn Injuries2017

Effects of different duration exercise programs in children with severe burns.

Robert P Clayton, Paul Wurzer, Clark R Andersen, Ronald P Mlcak, David N Herndon, Oscar E Suman

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Burns : journal of the International Society for Burn Injuries, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 3 pooled it
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 3 syntheses or guidelines pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Guideline
  4. Trial
  5. Trial
  6. Key Exercise Concepts in the Rehabilitation from Severe Burns.Physical medicine and rehabilitation clinics of North America · 2023
    Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Rehabilitative Exercise Training for Burn Injury.Sports medicine (Auckland, N.Z.) · 2021
    Review
  12. Current problems in burn hypermetabolism.Current problems in surgery · 2020
    Review
  13. Article
  14. Cardiovascular Effect of Varying Interval Training Frequency in Rehabilitation of Severely Burned Children.Journal of burn care & research : official publication of the American Burn Association · 2019
    Article
  15. Rehabilitation Exercise Increases Physical Activity Levels in Severely Burned Children While Improving Aerobic Exercise Capacity and Strength.Journal of burn care & research : official publication of the American Burn Association · 2018
    Article
  16. Burn Injury May Have Age-Dependent Effects on Strength and Aerobic Exercise Capacity in Males.Journal of burn care & research : official publication of the American Burn Association · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Robert P ClaytonShriners Hospitals for Children(®)-Galveston, University of Texas Medical Branch, Galveston, TX, USA; The Institute for Translational Sciences, University of Texas Medical Branch, Galveston, TX, USA. Electronic address: rpclayto@utmb.edu.
Paul WurzerShriners Hospitals for Children(®)-Galveston, University of Texas Medical Branch, Galveston, TX, USA; Department of Surgery, University of Texas Medical Branch, Galveston, TX, USA; Division of Plastic, Aesthetic and Reconstructive Surgery, Department of Surgery, Medical University of Graz, Graz, Austria.
Clark R AndersenShriners Hospitals for Children(®)-Galveston, University of Texas Medical Branch, Galveston, TX, USA; Department of Surgery, University of Texas Medical Branch, Galveston, TX, USA.
Ronald P MlcakShriners Hospitals for Children(®)-Galveston, University of Texas Medical Branch, Galveston, TX, USA.
David N HerndonShriners Hospitals for Children(®)-Galveston, University of Texas Medical Branch, Galveston, TX, USA; The Institute for Translational Sciences, University of Texas Medical Branch, Galveston, TX, USA; Department of Surgery, University of Texas Medical Branch, Galveston, TX, USA.
Oscar E SumanShriners Hospitals for Children(®)-Galveston, University of Texas Medical Branch, Galveston, TX, USA; Department of Surgery, University of Texas Medical Branch, Galveston, TX, USA. Electronic address: oesuman@utmb.edu.
Shriners Hospitals for Children - Galveston · USMedical University of Graz · AT

Funding

UTMB Clinical and Translational Science AwardUL1TR001439 · NCATS · UNIVERSITY OF TEXAS MED BR GALVESTON · PI URBAN, RANDALL J · 2015 to 2024
$40.0M
Project 9: The role of androgen/corticosteroid in fat, muscle and glucose metabolism of burn victimsP50GM060338 · NIGMS · UNIVERSITY OF TEXAS MEDICAL BR GALVESTON · PI HERNDON, DAVID N. · 2000 to 2017
$24.2M
MODULATION OF THE POSTBURN HYPERMETABOLIC RESPONSER01GM056687 · NIGMS · UNIVERSITY OF TEXAS MEDICAL BR GALVESTON · PI HERNDON, DAVID N. · 1998 to 2017
$9.0M
Oxandrolone and Exercise: A potent therapy in the rehabilitation from burnsR01HD049471 · NICHD · UNIVERSITY OF TEXAS MED BR GALVESTON · PI SUMAN-VEJAS, OSCAR E. · 2006 to 2019
$5.8M
POSTDOCTORAL TRAINING IN TRAUMA &BURNST32GM008256 · NIGMS · UNIVERSITY OF TEXAS MEDICAL BR GALVESTON · PI Celeste Campbell Finnerty, Oscar E. Suman-Vejas · 1990 to 2026
$4.0M
NCATS NIH HHS UL1 TR001439NICHD NIH HHS R01 HD049471NIGMS NIH HHS P50 GM060338NIGMS NIH HHS R01 GM056687NIGMS NIH HHS T32 GM008256
6 · The paper itself

Abstract

introductionBurns lead to persistent and detrimental muscle breakdown and weakness. Standard treatment at our institution includes a voluntary 12-week rehabilitative exercise program to limit and reverse the effects of increased muscle catabolism. In the present work, we investigated if different durations of exercise, 6 or 12 weeks, produce comparable improvements in muscle strength, body composition, and cardiopulmonary fitness.

methodsWe prospectively enrolled and randomized patients with ≥30% total body surface area (TBSA) burned to receive 6 or 12 weeks of exercise rehabilitation. Patients were evaluated for muscle strength, oxygen consumption capacity, and lean body mass at discharge (n=42) and after exercise. After 6 weeks (n=18) or 12 weeks (n=24) of exercise training, leg muscle strength was assessed as peak torque per body weight using a Biodex isokinetic dynamometer. Oxygen consumption capacity, measured as peak VO

resultsSignificant improvements in muscle strength, peak VO

conclusionThese data suggest that a 6-week rehabilitative exercise program is sufficient for improving muscle strength, body composition, and cardiopulmonary fitness in pediatric burn patients. However, continuation of at- or near-home cardiopulmonary training following the 6 weeks of at-hospital rehabilitation may be useful.

Indexed as

Cardiorespiratory FitnessMuscle StrengthOxygen ConsumptionAbsorptiometry, PhotonAdolescentBurnsChildExercise TestExercise TherapyFemaleHumansMaleMuscle, SkeletalTime FactorsTrauma Severity IndicesBurnsChildrenRehabilitationResistance exercise

Identifiers

PMID27908464
PMCPMC5422128
OpenAlexW2558332267

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.