ArticleBMC psychiatry2016
Smoking in pregnancy, adolescent mental health and cognitive performance in young adult offspring: results from a matched sample within a Finnish cohort.
Article in BMC psychiatry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.
- Psychiatric research in the Northern Finland Birth Cohort 1986 - a systematic review.International journal of circumpolar health · 2019Pooled it
- Urinary cotinine cut-offs for tobacco smoke exposure in pregnancy and associations with child intelligence quotient: A multi-cohort analysis.International journal of hygiene and environmental health · 2026Article
- Prenatal and postnatal drug exposure: focus on persistent central effects.Neural regeneration research · 2023Review
- Early-Life Environment Influence on Late-Onset Alzheimer's Disease.Frontiers in cell and developmental biology · 2022Review
- The Impact of Contextual, Maternal and Prenatal Factors on Receptive Language in a Chilean Longitudinal Birth Cohort.Child psychiatry and human development · 2021Article
- Prenatal Exposure to Tobacco and Offspring Neurocognitive Development in the Healthy Start Study.The Journal of pediatrics · 2020Observational
- Gestational exposure to nicotine and/or benzo[a]pyrene causes long-lasting neurobehavioral consequences.Birth defects research · 2019Article
- Polygenic Risk Score for Schizophrenia and Face-Processing Network in Young Adulthood.Schizophrenia bulletin · 2019Article
- Reasoning Abilities and Potential Correlates Among Jordanian School Children.Maternal and child health journal · 2018Article
Corrections and comments
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Authors and funding
12 authors at 7 institutions in 4 countries.
Funding
Abstract
backgroundThe association between prenatal exposure to maternal cigarette smoking (PEMCS) and adult cognition is debated, including if there are differences according to sex. We aimed to determine if there are associations between PEMCS and cognition in early adulthood in men and women and examine if observed associations were mediated by adolescent mental health factors that are associated with cognition, namely psychotic-like experiences (PLEs), inattention and hyperactivity, and other externalizing behaviors.
methodsParticipants were 471 individuals drawn from the general population-based Northern Finland 1986 Birth Cohort (NFBC 1986) followed up from pregnancy and birth to early adulthood; individuals with PEMCS were matched with those without PEMCS by socioeconomic and demographic factors. Cognitive performance in adulthood was assessed with a range of tests and their association with PEMCS was measured by sex using hierarchical linear regression, unadjusted and then controlling for potential confounders, mediators and moderators, including adolescent mental health factors.
resultsThere were no associations between PEMCS and cognitive scores in females. In males, there were associations with vocabulary (beta = -0.444, 95% CI: -0.783, -0.104) and matrix reasoning (beta = -0.379, 95% CI: -0.711, -0.047).
conclusionsWhile associations between PEMCS and cognition were limited, observed findings with measures of general intelligence in males contribute to suggestions of differences in response to PEMCS by sex. Furthermore, observed associations may be partly mediated by earlier inattention and hyperactivity. Findings add support to efforts aimed to eliminate smoking in pregnancy.
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