ArticlePloS one2016
Assessing Potentially Inappropriate Prescribing in Community-Dwelling Older Patients Using the Updated Version of STOPP-START Criteria: A Comparison of Profiles and Prevalences with Respect to the Original Version.
Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 50 citations in OpenAlex.
- Potentially Inappropriate Medication Use in Older Adults in Primary Care According to Four Explicit Criteria: Associations with Patient Factors.Medicina (Kaunas, Lithuania) · 2026Observational
- The University of Oklahoma Inpatient Spine Protocol: optimizing surgical outcomes through standardized perioperative care.GeroScience · 2026Review
- Functional Deprescribing: A Systems-Based Framework for Safe Medication Reduction.Integrative medicine (Encinitas, Calif.) · 2026Article
- Effect of Medication Management at Home via Pharmacist-Led Home Televisits: Protocol for a Cluster Randomized Controlled Trial.JMIR research protocols · 2025Article
- Polypharmacy and self-medication among older adults in Indian urban communities-a cross-sectional study.Scientific reports · 2025Article
- Article
- Comparing AGS Beers 2019, STOPP version 2, and EU(7)-PIM list in Portuguese older adults in primary health care.European journal of clinical pharmacology · 2024Article
- Potentially Inappropriate Prescribing and Potential Prescribing Omissions and Their Association with Adverse Drug Reaction-Related Hospital Admissions.Journal of clinical medicine · 2024Article
- Attitude towards deprescribing and its association with frailty and complexity of medication regimen: A survey of older inpatients in a district health board in New Zealand.BMC geriatrics · 2023Article
- Potentially Inappropriate Medication and Polypharmacy in Nursing Home Residents: A Cross-Sectional Study.Journal of clinical medicine · 2022Article
- Comparison of the prevalence and nature of potentially inappropriate medication use in geriatric outpatients between tertiary and community healthcare settings: a multicenter cross-sectional study.International journal of clinical pharmacy · 2022Article
- [Impact of pharmaceutical care in polymedicated patients admitted to a geriatric ward].Anales del sistema sanitario de Navarra · 2022Article
- Use of an Electronic Clinical Decision Support System in Primary Care to Assess Inappropriate Polypharmacy in Young Seniors With Multimorbidity: Observational, Descriptive, Cross-sectional Study.JMIR medical informatics · 2020Article
- Observational
- Potentially Inappropriate Prescribing and Related Hospital Admissions in Geriatric Patients: A Comparative Analysis between the STOPP and START Criteria Versions 1 and 2.Drugs & aging · 2019Article
- Medication use in older patients and age-blind approach: narrative literature review (insufficient evidence on the efficacy and safety of drugs in older age, frequent use of PIMs and polypharmacy, and underuse of highly beneficial nonpharmacological strategies).European journal of clinical pharmacology · 2019Review
- Polypharmacy in older patients at primary care units in Brazil.International journal of clinical pharmacy · 2019Article
- The impact of medication review with version 2 STOPP (Screening Tool of Older Person's Prescriptions) and START (Screening Tool to Alert doctors to Right Treatment) criteria in a French nursing home: a 3-month follow-up study.Therapeutic advances in drug safety · 2019Article
- Prevalence of potentially inappropriate prescribing in older people in primary care and its association with hospital admission: longitudinal study.BMJ (Clinical research ed.) · 2018Article
- Hospital readmissions, mortality and potentially inappropriate prescribing: a retrospective study of older adults discharged from hospital.British journal of clinical pharmacology · 2018Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Emerging and changing evidence made it necessary to update STOPP-START criteria, and version 2 was published recently. In this study the objectives were to determine the prevalence of potentially inappropriate medication prescribing (PIM) in primary care using STOPP versions 1 (v1) and 2 (v2), as well as 2012 AGS Beers criteria, and analyze the factors associated with inappropriate prescribing according to STOPP/START v2. A cross-sectional study was carried out including community-dwelling older adults over the age of 65. Sociodemographic, clinical, functional and comprehensive drug therapy data were collected. The primary endpoint was the percentage of patients receiving at least one PIM. This variable was measured using three tools: STOPP v1, 2012 AGS Beers criteria and STOPP v2. Similarly, the percentage of patients receiving at least one potential prescribing omission (PPO) was calculated using START versions 1 and 2. A total of 1,615 prescriptions were reviewed. The median number of medications per patient was 7.1 drugs (±3.8). The prevalence of elderly people exposed to polypharmacy (≥5 medications) was 72.9%, whereas 28.4% of the participants took ≥10 drugs regularly. PIM were present in 18.7%, 37.3% and 40.4% of participants, according to the STOPP v1, 2012 Beers criteria and STOPP v2, respectively. According to STOPP v2, the number of medications taken (OR: 1.14, 1.06-1.25), the presence of a psychological disorder (OR: 2.22, 1.13-4.37) and insomnia (OR: 3.35, 1.80-6.32) were risk factors for taking a PIM. The prevalence of PPOs was 34.7% and 21.8% according to version 1 and 2, respectively. In conclusion, STOPP-START criteria have been remarkably modified, which is evidenced by the different prevalence rates detected using version 2, as compared to version 1. In fact, the level of agreement between version 1 and the updated version is only moderate. Special attention should be paid on benzodiazepines, which keep being the most frequent PIM.
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