SynthesisPloS one2016
Carers' Medication Administration Errors in the Domiciliary Setting: A Systematic Review.
Synthesis in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed, 4 syntheses or guidelines pooled it, 68 citations in OpenAlex.
- Disruptions to safety and adaptations experienced by parents and caregivers who administered prescribed medicines to children at home: a systematic review using a framework synthesis.Frontiers in health services · 2026Pooled it
- Interventions to enhance in-home taking medication among older adults with multimorbidity/polypharmacy: a systematic review and meta-analysis.Frontiers in public health · 2025Pooled it
- Interventions to Reduce Pediatric Prescribing Errors in Professional Healthcare Settings: A Systematic Review of the Last Decade.Paediatric drugs · 2021Pooled it
- Interventions to Reduce Medication Dispensing, Administration, and Monitoring Errors in Pediatric Professional Healthcare Settings: A Systematic Review.Frontiers in pediatrics · 2021Pooled it
- A randomised trial of a psychoeducational intervention to improve home care safety for informal caregivers.Scientific reports · 2026Trial
- Pharmacists' Perspectives on Functional Medication-Use Challenges and Potential Adaptations for People with Disabilities in Saudi Arabia: A Qualitative Study.Healthcare (Basel, Switzerland) · 2026Article
- A qualitative exploration of informal carers' experiences with medication management and accessing community pharmacy support for people with long-term conditions.Exploratory research in clinical and social pharmacy · 2026Article
- Evolution of Clinical Fragility and Medication Burden in Children with Medical Complexity: A Longitudinal Cohort Study.Children (Basel, Switzerland) · 2026Article
- Observation and Prevention of Caregiver-Related Medication Errors in Community Pharmacies: A Cross-Sectional Study Across Urban, Town, and Rural Settings.Pharmaceuticals (Basel, Switzerland) · 2026Article
- 'We're the Eyes and Ears… out There': A Qualitative Exploration of the Perceptions and Experiences of Polypharmacy Amongst Home Care Providers.Health expectations : an international journal of public participation in health care and health policy · 2026Article
- Medication safety in family caregiving of older adults: home visits including interviews, observations, and medication reviews.BMC geriatrics · 2026Article
- Knowledge, Attitudes, and Behaviors of Italian Home Care Nurses: Factors Associated with Medication Error Prevention in a Nationwide Cross-Sectional Survey.Nursing reports (Pavia, Italy) · 2026Article
- Medication errors and associated serious outcomes in COVID-19 antivirals: a real-world study based on FDA Adverse Event Reporting System database.Therapeutic advances in drug safety · 2026Article
- Acceptability of supporting lay-carer administration of anticipatory subcutaneous medications at home: a qualitative study using the theoretical framework of acceptability.BMC palliative care · 2025Article
- Performance and Perceptions of Health Care Professionals Using an Immersive Virtual Reality Tool for Home Care Training: Observational Feasibility and Acceptability Study.JMIR serious games · 2025Article
- Article
- Understanding the Roles of over 65-Year-Old Male and Female Carers: A Comparative Analysis of Informal Caregiving.Geriatrics (Basel, Switzerland) · 2025Article
- Development of an eHealth Intervention in Pediatric Home Infusion Therapy: Interview Study of Needs and Preferences of Parents and Health Care Professionals.JMIR pediatrics and parenting · 2025Article
- Short-term outcome of personalized theory-based pharmaceutical care service on the medication administration problems of family caregivers: a pre-post intervention study.International journal of clinical pharmacy · 2025Article
- The resilience of parents and carers who administer medicines to children at home: a qualitative systematic review protocol.Systematic reviews · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeMedications are mostly taken in patients' own homes, increasingly administered by carers, yet studies of medication safety have been largely conducted in the hospital setting. We aimed to review studies of how carers cause and/or prevent medication administration errors (MAEs) within the patient's home; to identify types, prevalence and causes of these MAEs and any interventions to prevent them.
methodsA narrative systematic review of literature published between 1 Jan 1946 and 23 Sep 2013 was carried out across the databases EMBASE, MEDLINE, PSYCHINFO, COCHRANE and CINAHL. Empirical studies were included where carers were responsible for preventing/causing MAEs in the home and standardised tools used for data extraction and quality assessment.
resultsThirty-six papers met the criteria for narrative review, 33 of which included parents caring for children, two predominantly comprised adult children and spouses caring for older parents/partners, and one focused on paid carers mostly looking after older adults. The carer administration error rate ranged from 1.9 to 33% of medications administered and from 12 to 92.7% of carers administering medication. These included dosage errors, omitted administration, wrong medication and wrong time or route of administration. Contributory factors included individual carer factors (e.g. carer age), environmental factors (e.g. storage), medication factors (e.g. number of medicines), prescription communication factors (e.g. comprehensibility of instructions), psychosocial factors (e.g. carer-to-carer communication), and care-recipient factors (e.g. recipient age). The few interventions effective in preventing MAEs involved carer training and tailored equipment.
conclusionThis review shows that home medication administration errors made by carers are a potentially serious patient safety issue. Carers made similar errors to those made by professionals in other contexts and a wide variety of contributory factors were identified. The home care setting should be a priority for the development of patient safety interventions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.