ArticlePloS one2016
Dual Energy CT Pulmonary Angiography with 6g Iodine-A Propensity Score-Matched Study.
Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed, 20 citations in OpenAlex.
- Vascular attenuation and volumetric lung iodine density in dual-layer spectral CT pulmonary angiography: a randomized controlled trial comparing three contrast doses.European radiology · 2026Trial
- A randomised controlled trial comparing three clinical administration strategies in spectral detector CT pulmonary angiography with low contrast medium dose.European radiology · 2025Trial
- Assessment of an advanced virtual monoenergetic reconstruction technique in cerebral and cervical angiography with third-generation dual-source CT: Feasibility of using low-concentration contrast medium.European radiology · 2018Trial
- Contrast medium dose optimization in the era of multi-energy CT.Japanese journal of radiology · 2025Review
- Lung Dysfunction and Chronic Kidney Disease: A Complex Network of Multiple Interactions.Journal of personalized medicine · 2023Review
- Additive value of split-bolus single-phase CT scan protocol for preoperative assessment of lung cancer patients referred for video-assisted thoracic surgery.Radiological physics and technology · 2019Article
- Dual energy computed tomography virtual monoenergetic imaging: technique and clinical applications.The British journal of radiology · 2019Review
- Correction: Dual Energy CT Pulmonary Angiography with 6g Iodine-A Propensity Score-Matched Study.PloS one · 2017Article
Corrections and comments
- Erratum issuedCorrection: Dual Energy CT Pulmonary Angiography with 6g Iodine-A Propensity Score-Matched Study.2017 · Keller, Dagmar [corrected to Keller, Dagmar I]
Authors and funding
8 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo evaluate the performance of low contrast media (CM) dose dual-energy computed tomography pulmonary angiography (CTPA) with advanced monoenergetic reconstructions in patients with suspected pulmonary embolism (PE). MATERIALS AND
methodsThe study had institutional review board approval; all patients gave written informed consent. Forty-one patients (25 men, 16 women, mean age 62.9±14.7 years) undergoing low CM dose (15ml, 6g iodine) dual-energy CTPA with advanced monoenergetic reconstructions were matched via propensity-scoring based on logistic regression analysis with a comparison group of 41 patients (24 men, 17 women, mean age 62.7±13.9 years) undergoing standard CM dose single-energy CTPA (80ml, 24g iodine). Subjective (noise, artifacts) and objective (attenuation, noise, contrast-to-noise ratio (CNR)) image quality was assessed by two blinded, independent readers. All patients underwent clinical follow-up after three months for evaluation of adverse events.
resultsInterrater agreement for subjective image quality in both groups ranged from fair to excellent (ICC: 0.46-0.84); agreement for objective image quality was excellent (ICC: 0.83-0.93). There was no significant difference regarding subjective noise (p = 0.15-0.72) and artifacts (p = 0.16-1) between the low and the standard CM dose group. There was no significant difference regarding CNR between the CM dose groups (p = 0.11-0.87). Seven of the 41 (17%) patients in the low and 5/41 (12%) in the standard CM dose group were diagnosed with PE (p = 0.32). No patient suffered from subsequent PE or PE-associated death during the follow-up period.
conclusionDual-energy CTPA with advanced monoenergetic reconstruction is feasible with 6g iodine and allows for the diagnosis and safe exclusion of central, lobar, and segmental PE.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.