ArticlePloS one2016
Explaining the Decline in Coronary Heart Disease Mortality in the Netherlands between 1997 and 2007.
Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 41 citations in OpenAlex.
- Public knowledge of risk factors and warning signs for cardiovascular disease among young and middle-aged adults in rural Tanzania.BMC public health · 2020Trial
- Enhancing Public Knowledge of Risk Factors and Warning Signs for Stroke and Heart Attack Through Home-Based Community Health Worker Interventions: A Cluster Randomized Trial.International journal of general medicine · 2025Article
- Sex Differences in the Primary Prevention of Cardiovascular Diseases in a Dutch Primary Care Setting.Global heart · 2024Article
- Explaining the Decline in Coronary Heart Disease Mortality Rate Using IMPACT Model: Estimation of the Changes in Risk Factors and Treatment Uptake in Iran between 2007 and 2016.ARYA atherosclerosis · 2023Article
- Is area-level socioeconomic deprivation associated with mortality due to circulatory system diseases in Poland?BMC public health · 2023Article
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- Long-Term Cause-Specific Mortality in Hodgkin Lymphoma Patients.Journal of the National Cancer Institute · 2021Article
- Effect of community-based lifestyle education intervention to reduce cardiovascular diseases risk factors among vulnerable population in Dodoma city, Tanzania: a cluster randomized controlled trial study protocol.Biology methods & protocols · 2021Article
- Epidemiology and pathophysiologic insights of coronary atherosclerosis relevant for contemporary non-invasive imaging.Cardiovascular diagnosis and therapy · 2020Review
- Pharmacist role to enhance the prescribing of hospital discharge medications for patients after heart attack.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2020Article
- Mortality after hospital admission for heart failure: improvement over time, equally strong in women as in men.BMC public health · 2020Article
- Explaining the increment in coronary heart disease mortality in Mexico between 2000 and 2012.PloS one · 2020Article
- Detecting Mortality Trends in the Netherlands Across 625 Causes of Death.International journal of environmental research and public health · 2019Article
- A computerised decision support system for cardiovascular risk management 'live' in the electronic health record environment: development, validation and implementation-the Utrecht Cardiovascular Cohort Initiative.Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation · 2019Article
- Trends in the risk of cardiovascular disease in women with breast cancer in a Dutch nationwide cohort study.BMJ open · 2019Article
- A cost-effectiveness threshold based on the marginal returns of cardiovascular hospital spending.Health economics · 2019Article
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- Article
- Clinical Profile and Management of Patients with Incident and Recurrent Acute Myocardial Infarction in Albania - a Call for More Focus on Prevention Strategies.Zdravstveno varstvo · 2017Article
Corrections and comments
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Authors and funding
12 authors at 7 institutions in 2 countries.
Funding
Abstract
objectiveWe set out to determine what proportion of the mortality decline from 1997 to 2007 in coronary heart disease (CHD) in the Netherlands could be attributed to advances in medical treatment and to improvements in population-wide cardiovascular risk factors.
methodsWe used the IMPACT-SEC model. Nationwide information was obtained on changes between 1997 and 2007 in the use of 42 treatments and in cardiovascular risk factor levels in adults, aged 25 or over. The primary outcome was the number of CHD deaths prevented or postponed.
resultsThe age-standardized CHD mortality fell by 48% from 269 to 141 per 100.000, with remarkably similar relative declines across socioeconomic groups. This resulted in 11,200 fewer CHD deaths in 2007 than expected. The model was able to explain 72% of the mortality decline. Approximately 37% (95% CI: 10%-80%) of the decline was attributable to changes in acute phase and secondary prevention treatments: the largest contributions came from treating patients in the community with heart failure (11%) or chronic angina (9%). Approximately 36% (24%-67%) was attributable to decreases in risk factors: blood pressure (30%), total cholesterol levels (10%), smoking (5%) and physical inactivity (1%). Ten% more deaths could have been prevented if body mass index and diabetes would not have increased. Overall, these findings did not vary across socioeconomic groups, although within socioeconomic groups the contribution of risk factors differed.
conclusionCHD mortality has recently halved in The Netherlands. Equally large contributions have come from the increased use of acute and secondary prevention treatments and from improvements in population risk factors (including primary prevention treatments). Increases in obesity and diabetes represent a major challenge for future prevention policies.
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