ArticlePloS one2016
The Predictive Role of Red Cell Distribution Width in Mortality among Chronic Kidney Disease Patients.
Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Prognostic value of RDW and its derivatives in ICU patients with hypertensive chronic kidney disease.BMC cardiovascular disorders · 2026Article
- Elevated red cell distribution width as a prognostic indicator in critically ill patients with atrial fibrillation and chronic kidney disease.BMC cardiovascular disorders · 2026Article
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- Associations between red cell distribution width and in-hospital mortality in congestive heart failure patients with chronic obstructive pulmonary disease: a retrospective cohort study.Frontiers in medicine · 2025Article
- Correlation Between Red Blood Cell Distribution Width to Albumin Ratio and Cardiovascular Events in Maintenance Hemodialysis Patients.Journal of inflammation research · 2025Article
- Association of Red Blood Cell Distribution Width and Neutrophil-to-Lymphocyte Ratio with Calcification and Cardiovascular Markers in Chronic Kidney Disease.Metabolites · 2023Article
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- Red cell distribution width is associated with short-term mortality in critically ill patients with heart failure.ESC heart failure · 2022Article
- Influence of Red Blood Cell Distribution Width on All-Cause Death in Critical Diabetic Patients with Acute Kidney Injury.Diabetes, metabolic syndrome and obesity : targets and therapy · 2022Article
- Red Blood Cell Distribution Width Is Associated with Deterioration of Renal Function and Cardiovascular Morbidity and Mortality in Patients with Diabetic Kidney Disease.Life (Basel, Switzerland) · 2020Article
- Ancestry-specific associations identified in genome-wide combined-phenotype study of red blood cell traits emphasize benefits of diversity in genomics.BMC genomics · 2020Article
- Hematological parameters and all-cause mortality: a prospective study of older people.Aging clinical and experimental research · 2018Article
- Red cell distribution width and renal outcome in patients with non-dialysis-dependent chronic kidney disease.PloS one · 2018Observational
- Red cell distribution width associated with adverse cardiovascular outcomes in patients with chronic kidney disease.BMC nephrology · 2017Article
- Red cell distribution width predicts incident dipstick albuminuria in Korean adults without chronic kidney disease.Kidney research and clinical practice · 2017Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRecently, accumulating evidence has demonstrated that RDW independently predicts clinically important outcomes in many populations. However, the role of RDW has not been elucidated in chronic kidney disease (CKD) patients. We conducted the present study with the aim to evaluate the predictive value of RDW in CKD patients.
methodsA retrospective observational cohort study of 1075 stage 3-5 CKD patients was conducted in a medical center. The patients' baseline information included demographic data, laboratory values, medications, and comorbid conditions. The upper limit of normal RDW value (14.9%) was used to divide the whole population. Multivariate Cox regression analysis was used to determine the independent predictors of mortality.
resultsOf the 1075 participants, 158 patients (14.7%) died over a mean follow-up of approximately 2.35 years. The crude mortality rate was significantly higher in the high RDW group (high RDW group, 22.4%; low RDW group 11%, p <0.001). From the adjusted model, the high RDW group was correlated with a hazard ratio of 2.19 for overall mortality as compared with the low RDW group (95% CI = 1.53-3.09, p<0.001). In addition, the high RDW group was also associated with an increased risk for cardiovascular disease (HR = 2.28, 95% CI = 1.14-4.25, p = 0.019) and infection (HR = 1.9, 95% CI = 1.15-3.14, p = 0.012)) related mortality in comparison with the low RDW group.
conclusionsIn stage 3-5 CKD patients, RDW was associated with patient mortality of all-cause, cardiovascular disease and infection. RDW should be considered as a clinical predictor for mortality when providing healthcare to CKD patients.
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