Evidence map›Paper›PMID 27906155›Full record

ArticleRevista espanola de salud publica2016

[Prevalence of Hypothyroidism in Andalusia, Spain, Determined by Thyroid Hormone Comsumption].

José Escribano-Serrano, José Mancera-Romero, Vanessa Santos-Sánchez, Carolina Payá-Giner, Mª Isabel Méndez-Esteban, Antonio García-Bonilla, Manuela Márquez-Ferrando, Antonio Hormigo-Pozo, Alfredo Michán-Doña

Abstract read
In one paragraph

Article in Revista espanola de salud publica, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.2field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

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  9. Mood Disorders in Levothyroxine-Treated Hypothyroid Women.International journal of environmental research and public health · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

José Escribano-SerranoUnidad de Gestión Clínica de San Roque. Área de Gestión Sanitaria Campo de Gibraltar. Cádiz. España.
José Mancera-RomeroUnidad de Gestión Clínica Ciudad Jardín. Distrito de Atención Primaria Málaga-Guadalhorce. Málaga. España.
Vanessa Santos-SánchezFundación para la la Gestión de la Investigación Biomédica Cádiz. Cádiz. España.
Carolina Payá-GinerUnidad de Gestión Clínica Farmacia. Área de Gestión Sanitaria Campo de Gibraltar. Cádiz. España.
Mª Isabel Méndez-EstebanUnidad de Gestión Clínica Farmacia. Área de Gestión Sanitaria Campo de Gibraltar. Cádiz. España.
Antonio García-BonillaUnidad de Gestión Clínica Farmacia. Área de Gestión Sanitaria Norte de Cádiz. Cádiz. España.
Manuela Márquez-FerrandoUnidad de Gestión Clínica Farmacia. Distrito de Atención Primaria Cádiz-Bahía de Cádiz-La Janda. Cádiz. España.
Antonio Hormigo-PozoUnidad de Gestión Clínica Puerta Blanca. DAP Málaga-Guadalhorce. Málaga. España.
Alfredo Michán-DoñaUnidad de Gestión Clínica Medicina Interna-Dermatología. AGS Norte de Cádiz. Hospital de Jerez. Departamento de Medicina. Facultad de Medicina. Cádiz. España.
Universidad de Cádiz · ESClínica Girona · ESHospital Regional Universitario de Málaga · ESClínica Santa María · COFundación Para la Gestión de la Investigación Biomédica de Cádiz · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveHypothyroidism is the most common condition linked to a hormone deficiency, nevertheless data on its prevalence are scarce in Spain. For that reason, we have estimated its prevalence through the registration of patients who had used thyroid hormones in Andalusia (South Spain).

methodsData of patients who had withdrawn levothyroxine under the public system during 2014 from the base of the Andalusian Health Service were considered. Prevalence were calculated with confidence intervals of 95% for each management area, stratified by sex and age groups, and differences between them were evaluated.

results321,368 people (98% older than 18 years and 83% female) were identified as levothyroxine users and a prevalence of hypothyroidism of 3.95% (95%CI:3.94-3.96) was estimated for the general population. The condition was more common in females, in the older 18 years 7.81% (95%CI:7.80 to 7.82) compared to males 1.75% (95%CI:1.73-1.77) with a ratio of 4.5-fold. It increases in the population of women older than 45 years, 10.32% (95%CI:10.30-0.32) and in the over 60 years 11.37% (95%CI: 11.35-11.40). The prevalence in adult women in the western provinces is 7.38% (95%CI:7.36-7.40), in the eastern provinces 8.59% (95%CI:8.57-8.62) and in coastal areas 6.70% (95%CI: 6.68-6.72) compared to the mountainous ones, which is 8.91% (95%CI:8.88-8.94).

conclusionsThe results denote a high prevalence of hypothyroidism in the adult population of Andalusia compared to the nearby countries, with a clear increased associated with females and age. Furthermore, the prevalence of the illness presents also a geographically-related variability.

Indexed as

AdolescentAdultAgedAged, 80 and overAge FactorsFemaleHumansHypothyroidismMaleMiddle AgedPrevalenceRegistriesSex FactorsSpainThyroxineYoung AdultThyroxineGeographic FactorsHypothyroidismPharmacoepidemiologyPrevalenceSex RatioSpainThyroxine

Identifiers

PMID27906155
PMCPMC11587242
OpenAlexW2560485144

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.