Evidence map›Paper›PMID 27905869›Full record

ArticleRadiation research2016

Neurogenic Effects of Low-Dose Whole-Body HZE (Fe) Ion and Gamma Irradiation.

Tara B Sweet, Sean D Hurley, Michael D Wu, John A Olschowka, Jacqueline P Williams, M Kerry O'Banion

Open access · greenAbstract read
In one paragraph

Article in Radiation research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.3field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Radiotherapy for non-cancer diseases: benefits and long-term risks.International journal of radiation biology · 2024
    Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Long-Term Sex- and Genotype-Specific Effects ofInternational journal of molecular sciences · 2021
    Article
  10. Article
  11. Space Radiation Biology for "Living in Space".BioMed research international · 2020
    Review
  12. Space-likeScientific reports · 2019
    Article
  13. Review
  14. Central Nervous System Responses to Simulated Galactic Cosmic Rays.International journal of molecular sciences · 2018
    Review
  15. Whole-BodyInternational journal of molecular sciences · 2018
    Article
  16. Whole-Body Exposure toRadiation research · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Tara B SweetaDepartment of Neuroscience, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642.
Sean D HurleyaDepartment of Neuroscience, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642.
Michael D WuaDepartment of Neuroscience, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642.
John A OlschowkaaDepartment of Neuroscience, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642.
Jacqueline P Williamsb   Department of Environmental Medicine, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642.
M Kerry O'BanionaDepartment of Neuroscience, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642.
University of Rochester · US

Funding

Universiity of Rochester Center for Medical Countermeasures against RadiationU19AI091036 · NIAID · UNIVERSITY OF ROCHESTER · PI WILLIAMS, JACQUELINE PATRICIA · 2010 to 2014
$15.6M
NIAID NIH HHS U19 AI091036
6 · The paper itself

Abstract

Understanding the dose-toxicity profile of radiation is critical when evaluating potential health risks associated with natural and man-made sources in our environment. The purpose of this study was to evaluate the effects of low-dose whole-body high-energy charged (HZE) iron (Fe) ions and low-energy gamma exposure on proliferation and differentiation of adult-born neurons within the dentate gyrus of the hippocampus, cells deemed to play a critical role in memory regulation. To determine the dose-response characteristics of the brain to whole-body Fe-ion vs. gamma-radiation exposure, C57BL/6J mice were irradiated with 1 GeV/n Fe ions or a static

Indexed as

AnimalsDose-Response Relationship, RadiationDoublecortin ProteinGamma RaysIronMaleMiceMice, Inbred C57BLNeurogenesisTime FactorsWhole-Body IrradiationDcx protein, mouseDoublecortin ProteinIron

Identifiers

PMID27905869
PMCPMC5240657
OpenAlexW2559401980

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.