Evidence map›Paper›PMID 27905472›Full record

ArticleScientific reports2016

Electrochemical communication with the inside of cells using micro-patterned vertical carbon nanofibre electrodes.

F J Rawson, M T Cole, J M Hicks, J W Aylott, W I Milne, C M Collins, S K Jackson, N J Silman, P M Mendes

Abstract read
In one paragraph

Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Just a little prick: careful cell contacts enabled by ceramic nanostraws.Pflugers Archiv : European journal of physiology · 2026
    Article
  2. Article
  3. High-Aspect-Ratio Nanostructured Surfaces as Biological Metamaterials.Advanced materials (Deerfield Beach, Fla.) · 2020
    Review
  4. Electrochemical Response ofBiosensors · 2019
    Article
  5. Interfacing Cells with Vertical Nanoscale Devices: Applications and Characterization.Annual review of analytical chemistry (Palo Alto, Calif.) · 2018
    Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

F J RawsonSchool of Pharmacy, University of Nottingham, Nottingham, NG7 2RD, United Kingdom.
M T ColeElectrical Engineering Division, Department of Engineering, University of Cambridge, Cambridge, CB3 0FA, United Kingdom.
J M HicksSchool of Pharmacy, University of Nottingham, Nottingham, NG7 2RD, United Kingdom.
J W AylottSchool of Pharmacy, University of Nottingham, Nottingham, NG7 2RD, United Kingdom.
W I MilneElectrical Engineering Division, Department of Engineering, University of Cambridge, Cambridge, CB3 0FA, United Kingdom.
C M CollinsElectrical Engineering Division, Department of Engineering, University of Cambridge, Cambridge, CB3 0FA, United Kingdom.
S K JacksonSchool of Biomedical &Healthcare Sciences, University of Plymouth, Portland Square, Drake Circus, Plymouth, Devon PL4 8AA, United Kingdom.
N J SilmanPublic Health England, Porton Down, Salisbury, SP4 OJG, United Kingdom.
P M MendesSchool of Chemical Engineering, University of Birmingham, Edgbaston, Birmingham, B15 2TT, United Kingdom.

Funding

Biotechnology and Biological Sciences Research Council BB/L017059/1
6 · The paper itself

Abstract

With the rapidly increasing demands for ultrasensitive biodetection, the design and applications of new nano-scale materials for development of sensors based on optical and electrochemical transducers have attracted substantial interest. In particular, given the comparable sizes of nanomaterials and biomolecules, there exist plenty of opportunities to develop functional nanoprobes with biomolecules for highly sensitive and selective biosensing, shedding new light on cellular behaviour. Towards this aim, herein we interface cells with patterned nano-arrays of carbon nanofibers forming a nanosensor-cell construct. We show that such a construct is capable of electrochemically communicating with the intracellular environment.

Identifiers

PMID27905472
PMCPMC5131336

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.