Evidence map›Paper›PMID 27905352›Full record

ArticleRevista espanola de salud publica2016

[Future Perspective of Pharmacoepidemiology in the "Big Data Era" and the Growth of Information Sources].

Diego Macías Saint-Gerons, César de la Fuente Honrubia, Fernando de Andrés Trelles, Ferrán Catalá-López Catalá-López

Abstract read
In one paragraph

Article in Revista espanola de salud publica, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Diego Macías Saint-GeronsDivisión de Farmacoepidemiología y Farmacovigilancia. Agencia Española de Medicamentos y Productos Sanitarios (AEMPS). Madrid. España.dmacias.sg@gmail.com.
César de la Fuente HonrubiaÁrea de Estabilidad Presupuestaria. Subdirección General de Análisis Presupuestario y Organización Institucional del Sector Público Autonómico. Secretaría General de Coordinación Autonómica y Local. Ministerio de Hacienda y Administraciones Públicas. Madrid. España.
Fernando de Andrés TrellesDepartamento de Farmacología. Facultad de Medicina. Universidad Complutense de Madrid. España.
Ferrán Catalá-López Catalá-LópezClinical Epidemiology Program, Ottawa Hospital Research Institute (OHRI). Ottawa. Ontario. Canadá.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The arrival of new drug into the market requires many years of previous research along with the need of continuous evaluation throughout the lifetime of the drug. This warrants pharmacoepidemiological research which may be defined as the study of the use and the effects of drugs in large populations. Nowadays this type of research seems more feasible thanks to the massive expansion of the information sources and data (e.g: clinical patient registries, electronic medical records). However there is a risk of information overload, fragmented evidence and given the enthusiasm aroused by the "Big Data", it must be emphasized that its nature is mainly observational, and therefore subject to bias and confusion. The application of epidemiological methods in this scenario seems essential for any analysis. In short, the management and use of these data sources to generate useful information expansion is the next challenge for the application of research methods in modern pharmacoepidemiology.

Indexed as

Datasets as TopicBiasElectronic Health RecordsHumansPharmacoepidemiologyRegistriesResearch DesignInformation Systems (1966-1968)Medical InformaticsMedical RecordsPharmacoepidemiologyPrescription DrugsRegistriesTechnology, Pharmaceutical

Identifiers

PMID27905352
PMCPMC11587360

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.