ArticleJournal of research in medical sciences : the official journal of Isfahan University of Medical Sciences2016
The relationship between Vitamin D, clinical outcomes and mortality rate in ICU patients: A prospective observational study.
Article in Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.
- Vitamin D supplementation and mortality among critically ill adults: a systematic review and meta-analysis.Frontiers in nutrition · 2026Pooled it
- Fat-soluble vitamins as biomarkers of nutritional status and their relation with complications in polytrauma patients.Nutrition and health · 2025Observational
- Low plasma vitamin D is associated with increased 28-day mortality and worse clinical outcomes in critically ill patients.BMC nutrition · 2024Article
- Vitamin D status and its influence on outcomes following major burn injury and critical illness.Burns & trauma · 2018Review
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAccording to the high prevalence of Vitamin D deficiency, a few studies have been conducted to clarify the relationship between 25-hydroxyvitamin D (25(OH)D) and clinical outcomes in critically ill patients. The objective of this study was to determine this probable association. MATERIALS AND
methodsSerum 25(OH)D, C-reactive protein, malnutrition measurements, and Intensive Care Unit (ICU)-acquired infection from 185 patients in ICU were assessed in the first 24 h of admission and they were followed for the other outcomes.
resultsAbout 93.5% of patients were classified as deficient and insufficient while the others were categorized in sufficient group. 25(OH)D status was not significantly associated with mortality rate (
conclusionIn this study, we found that 25(OH)D insufficiency is common in ICU patients, but no significant association between low 25(OH)D levels and ICU outcomes were observed. Hence, because of vital roles of Vitamin D in human's body, comprehensive study should conduct to determine the decisive results.
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Registered trials
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