ArticleJournal of research in medical sciences : the official journal of Isfahan University of Medical Sciences2016
Evaluating the role of maternal folic acid supplementation in modifying the effects of methylenetetrahydrofolate reductase (C677T and A1298C) gene polymorphisms in oral cleft children.
Article in Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 authors at 4 institutions in 1 country.
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Abstract
backgroundWe studied the role of maternal folic acid supplementation in modifying the effects of methylenetetrahydrofolate reductase ( MATERIALS AND
methodsForty-seven newborn infants with orofacial cleft and their mothers were selected randomly. Mothers were matched regarding dietary folate intake. The genotyping on venous blood was carried out. Consistency between maternal and child genotypes was analyzed.
resultsGenotype consistency was not statistically significant in both C677T and A1298C gene variants (
conclusionMaternal folic acid consumption may not have any significant effect on modifying C677T and A1298C polymorphisms in children.
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