Evidence map›Paper›PMID 27904550›Full record

ReviewJournal of research in medical sciences : the official journal of Isfahan University of Medical Sciences2016

Serum leptin levels may be correlated with cerebral infarction.

Kun-Bin Li, Xian-Li Yao, Ping-Ge Sun, Zhi-Yuan Wu, Xiao-Xing Li, Jun-Qi Liu, Yi-Lan Li

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Kun-Bin LiDepartment of Neurological Rehabilitation, Zhengzhou Central Hospital, Zhengzhou University, Zhengzhou, People's Republic of China.
Xian-Li YaoDepartment of Neurological Rehabilitation, Zhengzhou Central Hospital, Zhengzhou University, Zhengzhou, People's Republic of China.
Ping-Ge SunDepartment of Neurological Rehabilitation, Zhengzhou Central Hospital, Zhengzhou University, Zhengzhou, People's Republic of China.
Zhi-Yuan WuDepartment of Neurological Rehabilitation, Zhengzhou Central Hospital, Zhengzhou University, Zhengzhou, People's Republic of China.
Xiao-Xing LiDepartment of Neurological Rehabilitation, Zhengzhou Central Hospital, Zhengzhou University, Zhengzhou, People's Republic of China.
Jun-Qi LiuDepartment of Neurological Rehabilitation, Zhengzhou Central Hospital, Zhengzhou University, Zhengzhou, People's Republic of China.
Yi-Lan LiDepartment of Rehabilitation Medicine, Zhengzhou Central Hospital, Zhengzhou University, Zhengzhou, People's Republic of China.
Zhengzhou Central Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo investigate the relation between serum leptin levels and cerebral infarction (CI) by meta-analysis. MATERIALS AND

methodsScientific literature databases were searched for studies published in Chinese and English. After retrieving relevant articles through database searches and screening using predefined selection criteria, high-quality studies related to our research topic were selected for inclusion in this meta-analysis. All statistical analyses were conducted using Comprehensive Meta-Analysis 2.0 (CMA 2.0, Biostat Inc., Englewood, New Jersey, USA).

resultsThe study results revealed that serum leptin levels were significantly higher in CI patients as compared to normal controls. The outcomes of subgroup analysis by ethnicity suggested that the serum leptin levels in CI patients were significantly higher than normal controls in both Asian and Caucasian populations. Further, subgroup analysis based on the detection method indicated that the serum leptin levels in CI patients were significantly higher compared with normal controls when measured by radioimmunoassay (RIA) but enzyme-linked immunosorbent assay (ELISA)-based measurements did not show such statistically significant differences.

conclusionOur meta-analysis results suggest that serum leptin levels in CI patients may be closely correlated with CI risks.

Indexed as

Case-control studycerebral infarction (CI)leptinmeta-analysisserum levels

Identifiers

PMID27904550
PMCPMC5122182
OpenAlexW2281247581

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.