Evidence map›Paper›PMID 27904528›Full record

ArticleArchives of medical science : AMS2016

Neuroprotective effects of erythropoietin against oxidant injury following brain irradiation: an experimental study.

Gamze Ugurluer, Aysegul Cebi, Handan Mert, Nihat Mert, Meltem Serin, Haldun Sukru Erkal

Open access · goldAbstract read
In one paragraph

Article in Archives of medical science : AMS, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Gamze UgurluerDepartment of Radiation Oncology, Faculty of Medicine, Acibadem University, Acibadem Adana Hospital, Adana, Turkey.
Aysegul CebiDepartment of Food Engineering, Faculty of Engineering, Giresun University, Giresun, Turkey.
Handan MertDepartment of Biochemistry, Faculty of Veterinary, Yuzuncu Yil University, Van, Turkey.
Nihat MertDepartment of Biochemistry, Faculty of Veterinary, Yuzuncu Yil University, Van, Turkey.
Meltem SerinDepartment of Radiation Oncology, Faculty of Medicine, Acibadem University, Acibadem Adana Hospital, Adana, Turkey.
Haldun Sukru ErkalDepartment of Radiation Oncology, Faculty of Medicine, Sakarya University, Sakarya, Turkey.
Van Yüzüncü Yıl Üniversitesi · TRAcıbadem Adana Hospital · TRAcıbadem University · TRGiresun University · TRSakarya University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionRadiation therapy (RT) is a major treatment modality, and the central nervous system is a dose-limiting organ in clinical RT. This experimental study aims to present the evaluation of the neuroprotective effects of erythropoietin (EPO) against oxidant injury following brain irradiation in rats. MATERIAL AND

methodsForty Wistar rats were randomly assigned to four groups (

resultsThe nitrite and MDA levels were higher in the RT group (2.10 ±0.62 ppm, 26.02 ±2.16 nmol/ml;

conclusionsThis study supports the probable neuroprotective effects of EPO against oxidant injury following brain irradiation in a rat model, presumably through decreasing free radical production and increasing expression of antioxidant enzymes.

Indexed as

brainerythropoietinirradiationneuroprotective effectsoxidant injury

Identifiers

PMID27904528
PMCPMC5108378
OpenAlexW2541991908

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.