ArticleArchives of medical science : AMS2016
Serum pregnancy-associated plasma protein A levels in the first, second and third trimester of pregnancy: relation to newborn anthropometric parameters and maternal tobacco smoking.
Article in Archives of medical science : AMS, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- The Consequences of Prenatal Tobacco Exposure: A Systematic Review of Birth Outcomes and Developmental Trajectories.Cureus · 2026Review
- Article
- Uterine artery doppler and pregnancy-associated plasma protein-A in pregnancies with fibroids.Clinics (Sao Paulo, Brazil) · 2025Article
- Customized birthweight standard for a Polish population.Archives of medical science : AMS · 2024Article
- The effect of active and passive maternal smoking before and during pregnancy on neonatal weight at birth.Archives of medical science : AMS · 2021Article
- Could first- and second-trimester biochemical markers for Down syndrome have a role in predicting intrahepatic cholestasis of pregnancy?Archives of medical science : AMS · 2018Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe purpose of this study was to evaluate the associations of the first, second and third trimester serum pregnancy-associated plasma protein A (PAPP-A) concentrations with neonatal anthropometric parameters. The effect of tobacco smoking during pregnancy on PAPP-A level was also studied. MATERIAL AND
methodsOne hundred and fifty healthy pregnant women were divided into smoking and tobacco-abstinent groups. Serum PAPP-A level was measured with the KRYPTOR rapid random-access immunoassay analyzer. The relationship between PAPP-A and newborn related outcome as well as markers of estimated intensity of cigarette smoking was evaluated by univariate and multivariate linear regression.
resultsPregnancy-associated plasma protein A concentration was positively correlated with birth weight in the first (β = 31.6;
conclusionsMaternal serum PAPP-A levels during gestation might be significant predictors for birth weight. Increased PAPP-A concentrations in the second and third trimester appeared to also be predictive for newborn body length and head circumference. Smoking alters maternal PAPP-A levels in all trimesters, with the greatest impact related to the number of cigarettes smoked per day.
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