Evidence map›Paper›PMID 27904505›Full record

ArticleThe journal of venomous animals and toxins including tropical diseases2016

Composition and biological activities of the aqueous extracts of three scleractinian corals from the Mexican Caribbean:

Alejandro García-Arredondo, Alejandra Rojas-Molina, César Ibarra-Alvarado, Fernando Lazcano-Pérez, Roberto Arreguín-Espinosa, Judith Sánchez-Rodríguez

Open access · goldAbstract read
In one paragraph

Article in The journal of venomous animals and toxins including tropical diseases, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
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  9. Review
  10. Conodipine-P1-3, the First Phospholipases AMolecular & cellular proteomics : MCP · 2019
    Article
  11. Article
  12. Hemolytic, anticancer and antigiardial activity ofThe journal of venomous animals and toxins including tropical diseases · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Alejandro García-ArredondoDepartamento de Investigación Química y Farmacológica de Productos Naturales, Facultad de Química, Universidad Autónoma de Querétaro, Querétaro, 76010 Mexico.
Alejandra Rojas-MolinaDepartamento de Investigación Química y Farmacológica de Productos Naturales, Facultad de Química, Universidad Autónoma de Querétaro, Querétaro, 76010 Mexico.
César Ibarra-AlvaradoDepartamento de Investigación Química y Farmacológica de Productos Naturales, Facultad de Química, Universidad Autónoma de Querétaro, Querétaro, 76010 Mexico.
Fernando Lazcano-PérezDepartamento de Ciencias de la Salud, Universidad Autónoma Metropolitana, Campus Iztapalapa, Mexico City, 09340 Mexico ; Instituto de Química, Universidad Nacional Autónoma de México, Mexico City, 04510 Mexico.
Roberto Arreguín-EspinosaInstituto de Química, Universidad Nacional Autónoma de México, Mexico City, 04510 Mexico.
Judith Sánchez-RodríguezUnidad Académica de Sistemas Arrecifales, Instituto de Ciencias del Mar y Limnología, Universidad Nacional Autónoma de México, Puerto Morelos, Quintana Roo 77500 Mexico.
Autonomous University of Queretaro · MXUniversidad Nacional Autónoma de México · MXUniversidad Autónoma Metropolitana · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundScleractinian corals (stony corals) are the most abundant reef-forming cnidarians found in coral reefs throughout the world. Despite their abundance and ecological importance, information about the diversity of their toxins and their biological activities is very scarce. In this study, the chemical composition and the biological activities of the aqueous extracts of

methodsToxicity of the extracts was assessed in crickets; the presence of cytolysins was detected by the hemolysis assay; the vasoconstrictor activity was determined by the isolated rat aortic ring assay; the nociceptive activity was evaluated by the formalin test. The presence of phospholipases A

resultsExtracts from the three species were toxic to crickets, induced hemolysis in human and rat erythrocytes, produced vasoconstriction on isolated rat aortic rings, and presented phospholipase A

conclusionThis study suggests that scleractinian corals produce low-molecular-weight peptides that are lethal to crickets and induce vasoconstriction.

Indexed as

HemolysisNociceptive responsePorites astreoidesPseudodiploria strigosaScleractiniaSiderastrea sidereaToxicityVasoconstriction

Identifiers

PMID27904505
PMCPMC5121987
OpenAlexW2556170400

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.