Evidence map›Paper›PMID 27904493›Full record

ArticleNeural regeneration research2016

Beta 2-adrenergic receptor activation enhances neurogenesis in Alzheimer's disease mice.

Gao-Shang Chai, Yang-Yang Wang, Amina Yasheng, Peng Zhao

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neural regeneration research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 52 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Gao-Shang ChaiDepartment of Basic Medicine, Wuxi Medical School, Jiangnan University, Wuxi, Jiangsu Province, China.ORCID 0000-0002-1943-3717
Yang-Yang WangDepartment of Basic Medicine, Wuxi Medical School, Jiangnan University, Wuxi, Jiangsu Province, China.
Amina YashengDepartment of Basic Medicine, Wuxi Medical School, Jiangnan University, Wuxi, Jiangsu Province, China.
Peng ZhaoDepartment of Basic Medicine, Wuxi Medical School, Jiangnan University, Wuxi, Jiangsu Province, China.
Jiangnan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Impaired hippocampal neurogenesis is one of the early pathological features of Alzheimer's disease. Enhancing adult hippocampal neurogenesis has been pursued as a potential therapeutic strategy for Alzheimer's disease. Recent studies have demonstrated that environmental novelty activates β

Indexed as

Alzheimer's diseaseamyloid βAPP/PS1 miceclenbuteroldendritic spinememorynerve regenerationneural regenerationneurogenesispostsynaptic density 95synapsin 1synaptophysinβ2-adrenoceptors

Identifiers

PMID27904493
PMCPMC5116841
OpenAlexW2544301137

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.