ArticleFood technology and biotechnology2015
Facile and Cost-Effective Detection of Saxitoxin Exploiting Aptamer Structural Switching.
Article in Food technology and biotechnology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 16 citations in OpenAlex.
- Current Trends and New Challenges in Marine Phycotoxins.Marine drugs · 2022Review
- Electrochemical impedance biosensor for detection of saxitoxin in aqueous solution.Analytical and bioanalytical chemistry · 2021Article
- Emerging Optical Materials in Sensing and Discovery of Bioactive Compounds.Sensors (Basel, Switzerland) · 2021Review
- Nuclease-assisted target recycling signal amplification strategy for graphene quantum dot-based fluorescent detection of marine biotoxins.Mikrochimica acta · 2021Article
- Structural characterization of the saxitoxin-targeting APTSTX1 aptamer using optical tweezers and molecular dynamics simulations.PloS one · 2019Article
- Review
- Aptamer-Based Biosensors to Detect Aquatic Phycotoxins and Cyanotoxins.Sensors (Basel, Switzerland) · 2018Review
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A simple method to detect saxitoxin (STX), one of the main components of the paralytic shellfish poison from red tide, has been developed. By using a next generation dye for double-stranded DNA we were able to differentiate fluorescence from STX-binding aptamers when exposed to different concentrations of STX, suggesting a change in aptamer folding upon target binding. The developed method is extremely rapid, only requiring small sample volumes, with quantitative results in the concentration range of 15 ng/mL to 3 µg/mL of STX, with a detection limit of 7.5 ng/mL.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.