Evidence map›Paper›PMID 27903841›Full record

ArticleIntegrative cancer therapies2017

Influence of a Moderate-Intensity Exercise Program on Early NK Cell Immune Recovery in Pediatric Patients After Reduced-Intensity Hematopoietic Stem Cell Transplantation.

Carolina Chamorro-Viña, Jaime Valentín, Lucía Fernández, Marta González-Vicent, Margarita Pérez-Ruiz, Alejandro Lucía, S Nicole Culos-Reed, Miguel Ángel Díaz, Antonio Pérez-Martínez

Open access · goldAbstract read
In one paragraph

Article in Integrative cancer therapies, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 3 pooled it
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 3 syntheses or guidelines pooled it, 31 citations in OpenAlex.

  1. Pooled it
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  15. The VIE study: feasibility of a physical activity intervention in a multidisciplinary program in children with cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2020
    Article
  16. Review
  17. Dietary and Exercise Interventions for Pediatric Oncology Patients: The Way Forward.Journal of the National Cancer Institute. Monographs · 2019
    Review
  18. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 2 countries.

Carolina Chamorro-Viña1 Faculty of Kinesiology, University of Calgary, Calgary, Alberta, Canada.
Jaime Valentín2 Innate Immune Research Group, IdiPAZ, Madrid, Spain.
Lucía Fernández3 Cancer Research National Centre, Madrid, Spain.
Marta González-Vicent4 Hospital Universitario Niño Jesús, Madrid, Spain.
Margarita Pérez-Ruiz5 Universidad Europea de Madrid, Madrid, Spain.
Alejandro Lucía5 Universidad Europea de Madrid, Madrid, Spain.
S Nicole Culos-Reed1 Faculty of Kinesiology, University of Calgary, Calgary, Alberta, Canada.
Miguel Ángel Díaz4 Hospital Universitario Niño Jesús, Madrid, Spain.
Antonio Pérez-Martínez7 Hospital Infantil Universitario La Paz, Madrid, Spain.
Hospital Infantil Universitario Niño Jesús · ESUniversidad Europea de Madrid · ESUniversity of Calgary · CAHospital La Paz Institute for Health Research · ESHospital Universitario La Paz · ESSpanish National Cancer Research Centre · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAfter allogeneic hematopoietic stem cell transplantation (HSCT), NK cell reconstitution, which is crucial for positive outcomes, is dominated by the CD56 PURPOSE: To determine the effects of a moderate-intensity exercise program on NK cell recovery early after HSCT and the feasibility of this intervention.

methodsSix children undergoing allogeneic HSCT were randomized to an exercise program (EP) or control (CT) group. The EP group performed a 10-week training combining in-hospital and home-based EP.

resultsWe observed a significant increase in the posttraining/pretraining ratio of the CD56

conclusionData suggest that a moderate-intensity EP program performed early after HSCT is feasible and might redistribute the CD56

Indexed as

AdolescentAdultCD56 AntigenChildExerciseExercise TherapyFemaleHematopoietic Stem Cell TransplantationHumansKiller Cells, NaturalMaleMiddle AgedYoung AdultCD56 Antigenallogeneic stem cell transplantationmoderate-intensity exercisenatural killer cell cytotoxicitynatural killer cells

Identifiers

PMID27903841
PMCPMC5739144
OpenAlexW2559545813

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.