Evidence map›Paper›PMID 27903784›Full record

ArticleJournal of the Royal Society, Interface2016

Terrain following and applications: Caenorhabditis elegans swims along the floor using a bump and undulate strategy.

Jinzhou Yuan, Hungtang Ko, David M Raizen, Haim H Bau

Abstract read
In one paragraph

Article in Journal of the Royal Society, Interface, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Microfluidic-AssistedCyborg and bionic systems (Washington, D.C.) · 2023
    Article
  2. Article
  3. Article
  4. Article
  5. Roll maneuvers are essential for active reorientation ofProceedings of the National Academy of Sciences of the United States of America · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jinzhou YuanDepartment of Mechanical Engineering and Applied Mechanics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Hungtang KoDepartment of Mechanical Engineering and Applied Mechanics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
David M RaizenDepartment of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Haim H BauDepartment of Mechanical Engineering and Applied Mechanics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA bau@seas.upenn.edu.ORCID 0000-0003-3815-5422

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Aric L Daul, Ann E. Rougvie · 2012 to 2026
$7.5M
Neuropeptidergic regulation of sleep in C. elegansR01NS088432 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI RAIZEN, DAVID MENASSAH · 2015 to 2019
$1.9M
Identification neurons controlling sleep/wake in the nematode C. elegansR21NS091500 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI FANG-YEN, CHRISTOPHER, RAIZEN, DAVID MENASSAH · 2015 to 2016
$429k
The Effect of Exercise on Frailty in C. elegansR03AG042690 · NIA · UNIVERSITY OF PENNSYLVANIA · PI BAU, HAIM H, RAIZEN, DAVID MENASSAH · 2013 to 2014
$148k
NIA NIH HHS R03 AG042690NIH HHS P40 OD010440NINDS NIH HHS R01 NS088432NINDS NIH HHS R21 NS091500
6 · The paper itself

Abstract

Nematodes such as Caenorhabditis elegans are heavier than water. When submerged in water, they settle to the bottom surface. Observations reveal that the animals do not lie flat on the bottom surface, but remain substantially suspended above the surface through continuous collisions with the surface, while maintaining their swimming gaits. Consequently, the swimming animals follow the bottom surface topography. When the bottom surface is inclined, the animals swim up or down along the incline. As the magnitude of the gravitational force can be easily estimated, this behaviour provides a convenient means to estimate the animal's propulsive thrust. The animals' tendency to follow the surface topography provides a means to control the swimmers' trajectories and direction of motion, which we demonstrate with a saw tooth-like ratchet that biases the animals to swim in a selected direction. The animals can also serve as surface topography probes since their residence time as a function of position provides information on surface features. Finally, we take advantage of surface following to construct a simple motility-based sorter that can sort animals based on genotype and state of health.

Indexed as

Models, BiologicalAnimalsCaenorhabditis elegansSwimmingCaenorhabditis elegansratchetsorterswimmingterrainthrust

Identifiers

PMID27903784
PMCPMC5134012

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.