Evidence map›Paper›PMID 27903660›Full record

ReviewEuropean respiratory review : an official journal of the European Respiratory Society2016

Future perspectives in pulmonary arterial hypertension.

Gérald Simonneau, Marius M Hoeper, Vallerie McLaughlin, Lewis Rubin, Nazzareno Galiè

Abstract readReview
In one paragraph

Review in European respiratory review : an official journal of the European Respiratory Society, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Pulmonary arterial hypertension: tailoring treatment to risk in the current era.European respiratory review : an official journal of the European Respiratory Society · 2017
    Review
  5. Pathobiology of pulmonary arterial hypertension: understanding the roads less travelled.European respiratory review : an official journal of the European Respiratory Society · 2017
    Review
  6. Metabolic dysfunction in pulmonary hypertension: from basic science to clinical practice.European respiratory review : an official journal of the European Respiratory Society · 2017
    Review
  7. Article
  8. The revolution of pulmonary arterial hypertension.European respiratory review : an official journal of the European Respiratory Society · 2016
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Gérald SimonneauUniversité Paris-Sud, Faculté de Médecine, Université Paris-Saclay, Le Kremlin-Bicêtre, France gerald.simonneau@bct.aphp.fr.
Marius M HoeperDept of Respiratory Medicine, Hannover Medical School and German Centre for Lung Research, Hannover, Germany.
Vallerie McLaughlinDept of Internal Medicine, University of Michigan Health System, Ann Arbor, MI, USA.
Lewis RubinDept of Medicine, University of California, San Diego, CA, USA.
Nazzareno GalièDept of Experimental, Diagnostic and Specialty Medicine (DIMES), University of Bologna, Bologna, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

While there have been advances in the field of pulmonary arterial hypertension (PAH), disease management remains suboptimal for many patients. The development of novel treatments and strategies can provide opportunities to target other mechanisms that play a role in the complex pathobiology of PAH outside of the three main pathophysiological pathways. In this review, we highlight some of the potential PAH therapies or techniques that are being, or have been, investigated in phase II clinical trials. This review also discusses potential points for consideration in the development of novel therapies that target putative disease mediators or modifiers.

Indexed as

Antihypertensive AgentsArterial PressureClinical Trials as TopicHumansHypertension, PulmonaryPulmonary ArteryTreatment OutcomeAntihypertensive Agents

Identifiers

PMID27903660
PMCPMC9487553

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.