Evidence map›Paper›PMID 27903614›Full record

Observational studyDiabetes care2017

Association Between Inpatient Sleep Loss and Hyperglycemia of Hospitalization.

Regina H DePietro, Kristen L Knutson, Lisa Spampinato, Samantha L Anderson, David O Meltzer, Eve Van Cauter, Vineet M Arora

Open access · bronzeAbstract readObservational Study
In one paragraph

Observational study in Diabetes care, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it, 66 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Observational
  11. Sleeping with one cerebrum open: patient and staff perceptions of sleep quality and quantity on an inpatient neurology unit.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2024
    Observational
  12. Observational
  13. Article
  14. Article
  15. Perspective: leveraging the electronic health record to improve sleep in the hospital.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2023
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Barriers to sleep in acute hospital settings.Sleep & breathing = Schlaf & Atmung · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Regina H DePietroStony Brook University School of Medicine, Stony Brook, NY.
Kristen L KnutsonUniversity of Chicago Sleep Metabolism and Health Center, Chicago, IL.
Lisa SpampinatoUniversity of Chicago Sleep Metabolism and Health Center, Chicago, IL.
Samantha L AndersonUniversity of Chicago Sleep Metabolism and Health Center, Chicago, IL.
David O MeltzerUniversity of Chicago Sleep Metabolism and Health Center, Chicago, IL.
Eve Van CauterUniversity of Chicago Sleep Metabolism and Health Center, Chicago, IL.
Vineet M AroraUniversity of Chicago Sleep Metabolism and Health Center, Chicago, IL varora@uchicago.edu.
University of Chicago · USStony Brook University · US

Funding

Research Design, Data, and Analytics CoreP30DK092949 · NIDDK · UNIVERSITY OF CHICAGO · PI ELBERT S. HUANG · 2011 to 2026
$10.0M
SIESTA (Sleep for Inpatients: Educating Staff to Act) - Resubmission 01R25HL116372 · NHLBI · UNIVERSITY OF CHICAGO · PI ARORA, VINEET · 2014 to 2017
$977k
Environment and Perceived Control: Improving Sleep in Hospitalized Older PatientsK23AG033763 · NIA · UNIVERSITY OF CHICAGO · PI ARORA, VINEET · 2009 to 2013
$762k
NHLBI NIH HHS R25 HL116372NIA NIH HHS K23 AG033763NIDDK NIH HHS P30 DK092949
6 · The paper itself

Abstract

objectiveTo determine whether inpatient sleep duration and efficiency are associated with a greater risk of hyperglycemia in hospitalized patients with and without diabetes. RESEARCH DESIGN AND

methodsIn this retrospective analysis of a prospective cohort study, medical inpatients ≥50 years of age were interviewed, and their charts were reviewed to obtain demographic data and diagnosis. Using World Health Organization criteria, patients were categorized as having normal blood glucose, impaired fasting blood glucose, or hyperglycemia based on morning glucose from the electronic health record. Wrist actigraphy measured sleep. Multivariable ordinal logistic regression models, controlling for subject random effects, tested the association between inpatient sleep duration and proportional odds of hyperglycemia versus impaired fasting blood glucose or impaired fasting blood glucose versus normal blood glucose in hospitalized adults.

resultsA total of 212 patients (60% female and 74% African American) were enrolled. Roughly one-third (73, 34%) had diabetes. Objective inpatient sleep measures did not differ between patients with or without diabetes. In ordinal logistic regression models, each additional hour of in-hospital sleep was associated with an 11% (odds ratio 0.89 [95% CI 0.80, 0.99]; P = 0.043) lower proportional odds of a higher glucose category the next morning (hyperglycemia vs. elevated and elevated vs. normal). Every 10% increase in sleep efficiency was associated with an 18% lower proportional odds of a higher glucose category (odds ratio 0.82 [95% CI 0.74, 0.89]; P < 0.001).

conclusionsAmong medical inpatients, both shorter sleep duration and worse sleep efficiency were independently associated with greater proportional odds of hyperglycemia and impaired fasting glucose.

Indexed as

HospitalizationActigraphyAgedBlood GlucoseFemaleHumansHyperglycemiaInpatientsLogistic ModelsMaleMiddle AgedPrediabetic StateProspective StudiesRetrospective StudiesSleep Initiation and Maintenance DisordersBlood Glucose

Identifiers

PMID27903614
PMCPMC5250691
OpenAlexW2557621730

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.