ReviewJournal of nanobiotechnology2016
A critical review of the current knowledge regarding the biological impact of nanocellulose.
Review in Journal of nanobiotechnology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
66 citing papers in PubMed.
- Nanocellulose as an Active Biointerface: Design Principles for Infection-Adaptive and Regenerative Biomaterials.Small (Weinheim an der Bergstrasse, Germany) · 2026Review
- From Colloids to Hydrogels: Concentration-Dependent Cytocompatibility of Carboxylated Cellulose Nanocrystals Prepared via Deep Eutectic Solvents.Langmuir : the ACS journal of surfaces and colloids · 2026Article
- Scoping Review of the Biomedical Investigations of Cellulose Nanocrystal-Based Hydrogels: A Critical Analysis of Current Evidence, Research Gaps and Future Perspectives.Gels (Basel, Switzerland) · 2026Review
- Article
- Emerging Biomedical Applications of Sustainable Cellulose Nanocrystal-Incorporated Hydrogels: A Scoping Review.Gels (Basel, Switzerland) · 2025Review
- Sustainable Farming: Nanofiber from the Pupunha Heart of Palm Sheath (Veterinary sciences · 2025Article
- Life-Cycle Risk Assessment of Second-Generation Cellulose Nanomaterials.Nanomaterials (Basel, Switzerland) · 2025Article
- Evaluation of the cyto- and genotoxicity of two types of cellulose nanomaterials using human intestinal cells and in vitro digestion simulation.Archives of toxicology · 2025Article
- Emerging Fluorescent Nanoparticles for Non-Invasive Bioimaging.Molecules (Basel, Switzerland) · 2024Review
- Fast, Easy, and Reproducible Fingerprint Methods for Endotoxin Characterization in Nanocellulose and Alginate-Based Hydrogel Scaffolds.Biomacromolecules · 2024Article
- One-Component Nanocomposites Made from Diblock Copolymer Grafted Cellulose Nanocrystals.Biomacromolecules · 2024Article
- Biopolymer-Based Nanomedicine for Cancer Therapy: Opportunities and Challenges.International journal of nanomedicine · 2024Review
- Nanocrystalline Cellulose as a Versatile Engineering Material for Extrusion-Based Bioprinting.Pharmaceutics · 2023Article
- Assessing the Genotoxicity of Cellulose Nanomaterials in a Co-Culture of Human Lung Epithelial Cells and Monocyte-Derived Macrophages.Bioengineering (Basel, Switzerland) · 2023Article
- Review
- Insight into the Latest Medical Applications of Nanocellulose.Materials (Basel, Switzerland) · 2023Review
- Sulfated endospermic nanocellulose crystals prevent the transmission of SARS-CoV-2 and HIV-1.Scientific reports · 2023Article
- Review on Hybrid Reinforced Polymer Matrix Composites with Nanocellulose, Nanomaterials, and Other Fibers.Polymers · 2023Review
- Inclusion of Soybean Hulls (Animals : an open access journal from MDPI · 2023Article
- Agarose/crystalline nanocellulose (CNC) composites promote bone marrow-derived mast cell integrity, degranulation and receptor expression but inhibit production ofFrontiers in bioengineering and biotechnology · 2023Article
6 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Several forms of nanocellulose, notably cellulose nanocrystals and nanofibrillated cellulose, exhibit attractive property matrices and are potentially useful for a large number of industrial applications. These include the paper and cardboard industry, use as reinforcing filler in polymer composites, basis for low-density foams, additive in adhesives and paints, as well as a wide variety of food, hygiene, cosmetic, and medical products. Although the commercial exploitation of nanocellulose has already commenced, little is known as to the potential biological impact of nanocellulose, particularly in its raw form. This review provides a comprehensive and critical review of the current state of knowledge of nanocellulose in this format. Overall, the data seems to suggest that when investigated under realistic doses and exposure scenarios, nanocellulose has a limited associated toxic potential, albeit certain forms of nanocellulose can be associated with more hazardous biological behavior due to their specific physical characteristics.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.