SynthesisCritical care (London, England)2016
Association between time of discharge from ICU and hospital mortality: a systematic review and meta-analysis.
Synthesis in Critical care (London, England), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Inhaled antibiotics for treating pneumonia in invasively ventilated patients in intensive care unit: a meta-analysis of randomized clinical trials with trial sequential analysis.Critical care (London, England) · 2024Pooled it
- Out-of-hours discharge from intensive care, in-hospital mortality and intensive care readmission rates: a systematic review and meta-analysis.Intensive care medicine · 2018Pooled it
- Weekend effect in emergency hospitalizations of older adults in Hong Kong.Scientific reports · 2026Article
- Prognostic Factors of 30-Day In-Hospital Mortality in Critically Ill Patients Receiving Continuous Renal Replacement Therapy.The journal of nursing research : JNR · 2026Observational
- Nighttime intensive care unit admission increased 30-day mortality in sepsis patients: a retrospective propensity-score matched analysis based on MIMIC-IV database.Scientific reports · 2026Article
- Intensive care unit caseload and workload and their association with outcomes in critically unwell patients: a large registry-based cohort analysis.Critical care (London, England) · 2024Article
- Unveiling the performance of the prehospital Rapid Emergency Medicine Score (pREMS): How the predictive score impacts in-hospital outcomes in traumatic brain injury (TBI): A retrospective observational cohort study.BMC emergency medicine · 2024Observational
- Outcomes of traumatically injured patients after nighttime transfer from the intensive care unit.Trauma surgery & acute care open · 2024Article
- Mortality and readmission rates of patients discharged in-hours and out-of-hours from a British ICU over a 3-year period.Scientific reports · 2022Article
- A retrospective observational study of daytime and nighttime transfers from the intensive care unit: through the lens of critical care response teams.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2021Observational
- Association between intensive care unit occupancy at discharge, afterhours discharges, and clinical outcomes: a historical cohort study.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2020Article
- Mortality in severely injured patients: nearly one of five non-survivors have been already discharged alive from ICU.BMC anesthesiology · 2020Article
- Acute respiratory compromise on hospital wards: Association between recent ICU discharge and outcome.Resuscitation · 2019Article
- Article
- A Shift in Time Saves …….Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2019Article
- Transfer Time from the Intensive Care Unit and Patient Outcome: A Retrospective Analysis from a Tertiary Care Hospital in India.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2019Article
- Risk Factors for 1-Year Mortality and Hospital Utilization Patterns in Critical Care Survivors: A Retrospective, Observational, Population-Based Data Linkage Study.Critical care medicine · 2019Observational
- Going back to the ward-transitioning care back to the ward team.Translational pediatrics · 2018Review
- Out-of-hours discharge from intensive care: certain about uncertainty.Intensive care medicine · 2018Article
- [Unplanned admission or readmission to the intensive care unit : Avoidable or fateful?]Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEpidemiological studies have provided inconsistent results on whether intensive care unit (ICU) discharge at night and on weekends is associated with an increased risk of mortality. This systematic review and meta-analysis aimed to determine whether ICU discharge time was associated with hospital mortality.
methodsThe PubMed, Embase, and Scopus databases were searched to identify cohort studies that investigated the effects of discharge from the ICU on weekends and at night on hospital mortality, with adjustments for the disease severity at ICU admission or discharge. The primary meta-analysis focused on the association between nighttime ICU discharge and hospital mortality. The secondary meta-analysis examined the association between weekend ICU discharge and hospital mortality. Odds ratios (ORs) with 95% confidence intervals (CIs) were pooled using a random-effects model.
resultsWe included 14 studies that assessed outcomes for nighttime versus daytime discharges among 953,312 individuals. Of these 14 studies, 5 evaluated outcomes for weekend versus weekday discharges (n = 70,883). The adjusted OR for hospital mortality was significantly higher among patients discharged during the nighttime, compared to patients discharged during the daytime (OR 1.31, 95% CI 1.25-1.38, P < 0.0001), and the studies exhibited low heterogeneity (I
conclusionsNighttime ICU discharge is associated with an increased risk of hospital mortality, while weekend ICU discharge is not. Given the methodological limitations and heterogeneity among the included studies, these conclusions should be interpreted with caution, and should be tested in further studies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.