Evidence map›Paper›PMID 27903083›Full record

ArticleAIDS care2017

Club drugs and alcohol abuse predicted dropout and poor adherence among methadone maintenance treatment patients in Guangzhou, China.

Di Liu, Jing Gu, Huifang Xu, Chun Hao, Mingxu Jiao, Xiao Zhang, Yuteng Zhao, Babbitt Andrew, Yuantao Hao

Registry-linked trialAbstract read
In one paragraph

Article in AIDS care, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04706624 (Screen, Treat and Retain Meth-using People With Opioid Use Disorders at Methadone Clinics), which is not on this map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04706624 nacompletednot on this mapstarted 2021, after this paper: background citation

Screen, Treat and Retain Meth-using People With Opioid Use Disorders at Methadone Clinics

TypeinterventionalSponsorHanoi Medical UniversityRan2021 to 2025Enrolled667ConditionsMethamphetamine Abuse, Opioid-use Disorder, HIV SeropositivityArmsContingency management (12 weeks), Contingency management (6 weeks), SMS reminders, Matrix only, Matrix + Contingency management
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Di Liua Department of Medical Statistics and Epidemiology , School of Public Health, Sun Yat-sen University , Guangzhou , People's Republic of China.
Jing Gua Department of Medical Statistics and Epidemiology , School of Public Health, Sun Yat-sen University , Guangzhou , People's Republic of China.
Huifang Xuc Department of HIV/AIDS Prevention and Control , Guangzhou Center for Disease Prevention and Control , Guangzhou , People's Republic of China.
Chun Haoa Department of Medical Statistics and Epidemiology , School of Public Health, Sun Yat-sen University , Guangzhou , People's Republic of China.
Mingxu Jiaoa Department of Medical Statistics and Epidemiology , School of Public Health, Sun Yat-sen University , Guangzhou , People's Republic of China.
Xiao Zhanga Department of Medical Statistics and Epidemiology , School of Public Health, Sun Yat-sen University , Guangzhou , People's Republic of China.
Yuteng Zhaoc Department of HIV/AIDS Prevention and Control , Guangzhou Center for Disease Prevention and Control , Guangzhou , People's Republic of China.
Babbitt Andrewa Department of Medical Statistics and Epidemiology , School of Public Health, Sun Yat-sen University , Guangzhou , People's Republic of China.
Yuantao Haoa Department of Medical Statistics and Epidemiology , School of Public Health, Sun Yat-sen University , Guangzhou , People's Republic of China.

Funding

Fogarty Global Health Fellows Coordinating CenterR25TW009340 · FIC · UNIV OF NORTH CAROLINA CHAPEL HILL · PI CHI, BENJAMIN H. · 2012 to 2016
$6.9M
Northern/Pacific Universities Global Health Research Training ConsortiumR25TW009345 · FIC · UNIVERSITY OF WASHINGTON · PI KOLARS, JOSEPH C., NERURKAR, VIVEK RAMCHANDRA · 2012 to 2016
$5.9M
FIC NIH HHS R25 TW009340FIC NIH HHS R25 TW009345
6 · The paper itself

Abstract

Club drugs and alcohol abuse are prevalent among methadone maintenance treatment (MMT) patients. However, little is known about the association between these abuse and treatment outcomes among MMT patients. The aim of this study was to examine the prevalence of club drugs and alcohol abuse among MMT patients and to investigate the associations between these abuse and treatment outcomes - dropout and poor adherence. In this one-year cohort study conducting in Guangzhou, China, data including background characteristics, club drugs use in the last six months, alcohol use history and treatment-related information was collected. Cox regression analyses and log-binomial regression analyses were applied to identify the associations between these abuse and dropout and poor adherence, respectively. Thirty-seven participants (9.2%) admitted to the use of at least one type of club drugs in the last six months and 88 (21.9%) were identified as alcohol abusers. Of all participants, 21.0% had dropped out of treatment and 27.7% exhibited poor adherence during the study period. Adjusting for significant background variables, use of at least one type of club drugs [hazards ratio (HR) = 1.90, 95% confidence interval (CI) = 1.01-3.56] and use of methamphetamine in the last six months (HR = 2.26, 95% CI = 1.15-4.43) significantly predicted dropout. Frequency of having six or more drinks on one drinking occasion when drinking [relative risk (RR) = 1.87, 95% CI = 1.16-2.95] significantly predicted poor adherence. Our findings indicated that club drugs and alcohol abuse predicted dropout and poor adherence among MMT patients. Early identification and intervention for the abuse should be taken into consideration when developing interventions tailored to improve treatment outcomes among MMT patients.

Indexed as

Designer DrugsDrug MonitoringAdultAlcohol DrinkingAlcoholismChinaCohort StudiesFemaleHumansMaleMethadoneNarcoticsOpiate Substitution TreatmentOpioid-Related DisordersPatient DropoutsDesigner DrugsMethadoneNarcoticsadherencealcoholclub drugsdropoutMethadone maintenance treatment

Identifiers

PMID27903083
PMCPMC7243263

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.