Evidence map›Paper›PMID 27902841›Full record

ArticleThe Journal of physiology2017

Dynamical effects of calcium-sensitive potassium currents on voltage and calcium alternans.

Matthew Kennedy, Donald M Bers, Nipavan Chiamvimonvat, Daisuke Sato

Abstract read
In one paragraph

Article in The Journal of physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. Atomistic mechanisms of the regulation of small-conductance CaProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  3. Article
  4. Review
  5. Dual effects of the small-conductance CaAmerican journal of physiology. Heart and circulatory physiology · 2023
    Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Sex-specific IHeart rhythm · 2021
    Article
  11. Small-conductance CaHeart rhythm · 2020
    Article
  12. Impact of IBiophysical journal · 2020
    Article
  13. A compartmentalized mathematical model of mouse atrial myocytes.American journal of physiology. Heart and circulatory physiology · 2020
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. HDAC Inhibition Improves the Sarcoendoplasmic Reticulum CaInternational journal of molecular sciences · 2018
    Article
  19. KThe Journal of physiology · 2017
    Article
  20. From channels to systems: CaThe Journal of physiology · 2017
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Matthew KennedyDepartment of Biomedical Engineering, University of California, Davis, CA, USA.ORCID 0000-0002-5792-8382
Donald M BersDepartment of Pharmacology, University of California, Davis, CA, USA.ORCID 0000-0002-2237-9483
Nipavan ChiamvimonvatDivision of Cardiovascular Medicine, Department of Internal Medicine, University of California, Davis, CA, USA.ORCID 0000-0001-9499-8817
Daisuke SatoDepartment of Pharmacology, University of California, Davis, CA, USA.ORCID 0000-0001-9341-0970

Funding

Functional Interactions of Cardiac Ion ChannelsR01HL085844 · NHLBI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI CHIAMVIMONVAT, NIPAVAN · 2007 to 2025
$7.3M
Translational Study of Cardiac DysfunctionR01HL085727 · NHLBI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI CHIAMVIMONVAT, NIPAVAN, SIRISH, PADMINI · 2008 to 2022
$5.7M
IONIC CONTROL OF CARDIAC MUSCLE CONTRACTION: EC COUPLINGR01HL030077 · NHLBI · UNIVERSITY OF CALIFORNIA RIVERSIDE · PI BERS, DONALD M · 1986 to 2018
$3.8M
Multi-scale Systems Model of Murine Heart FailureR01HL105242 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BERS, DONALD M, MCCULLOCH, ANDREW D. · 2012 to 2016
$3.5M
Decoding the enigma of cardiac amplificationR01HL137228 · NHLBI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI CHIAMVIMONVAT, NIPAVAN · 2017 to 2020
$2.2M
Modeling of Cardiac Calcium Dynamics; Ryanodine Receptor induced ArrhythmiasR00HL111334 · NHLBI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI SATO, DAISUKE · 2015 to 2017
$738k
Modeling of Cardiac Calcium Dynamics; Ryanodine Receptor induced ArrhythmiasK99HL111334 · NHLBI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI SATO, DAISUKE · 2012 to 2013
$194k
Metabolomics study in patients post myocardial infarctionI01CX001490 · VA · VA NORTHERN CALIFORNIA HEALTH CARE SYS · PI CHIAMVIMONVAT, NIPAVAN · 2017 to 2021
–
Regulation of ion channels in the heartI01BX000576 · VA · VA NORTHERN CALIFORNIA HEALTH CARE SYS · PI CHIAMVIMONVAT, NIPAVAN · 2009 to 2019
–
BLRD VA I01 BX000576CSRD VA I01 CX001490NHLBI NIH HHS K99 HL111334NHLBI NIH HHS R00 HL111334NHLBI NIH HHS R01 HL030077NHLBI NIH HHS R01 HL085727NHLBI NIH HHS R01 HL085844NHLBI NIH HHS R01 HL105242NHLBI NIH HHS R01 HL137228
6 · The paper itself

Abstract

key pointsA mathematical model of a small conductance Ca ABSTRACT: Cardiac alternans is a precursor to life-threatening arrhythmias. Alternans can be caused by instability of the membrane voltage (V

Indexed as

CalciumModels, BiologicalMyocytes, CardiacPotassium Channels, Calcium-ActivatedCalciumPotassium Channels, Calcium-Activatedcardiac alternanscardiac electrophysiologycardiac functioncardiac potassium current

Identifiers

PMID27902841
PMCPMC5374119

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.