ArticleMedicine2016
Severity of pulmonary emphysema and lung cancer: analysis using quantitative lobar emphysema scoring.
Article in Medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed.
- Predicting life-threatening hemoptysis in traumatic pulmonary parenchymal injury using computed tomography semi-automated lung volume quantification.Insights into imaging · 2024Article
- Analysis of clinical characteristics and prognosis of lung cancer patients with CPFE or COPD: a retrospective study.BMC pulmonary medicine · 2024Article
- Three-dimensional analysis reveals a high incidence of lung adenocarcinoma in the upper region.Surgery today · 2024Article
- Effect of emphysema on AI software and human reader performance in lung nodule detection from low-dose chest CT.European radiology experimental · 2024Article
- Quantifying emphysema in lung screening computed tomography with robust automated lobe segmentation.Journal of medical imaging (Bellingham, Wash.) · 2023Article
- Article
- Computed Tomography Features of Lung Structure Have Utility for Differentiating Malignant and Benign Pulmonary Nodules.Chronic obstructive pulmonary diseases (Miami, Fla.) · 2022Article
- From COPD to Lung Cancer: Mechanisms Linking, Diagnosis, Treatment, and Prognosis.International journal of chronic obstructive pulmonary disease · 2022Review
- Quantitative determination of pulmonary emphysema in follow-up LD-CTs of patients with COVID-19 infection.PloS one · 2022Article
- Article
- Computed tomography semi-automated lung volume quantification in SARS-CoV-2-related pneumonia.European radiology · 2021Article
- Comprehensive Perspective for Lung Cancer Characterisation Based on AI Solutions Using CT Images.Journal of clinical medicine · 2020Article
- Lung emphysema and lung cancer: what do we know about it?Annals of translational medicine · 2020Review
- Comparison between quantitative computed tomography, scintigraphy, and anatomical methods for prediction of postoperative FEVJournal of thoracic disease · 2020Article
- Regional emphysema score is associated with tumor location and poor prognosis in completely resected NSCLC patients.BMC pulmonary medicine · 2020Article
- Transbronchial biopsy from the upper pulmonary lobes is associated with increased risk of pneumothorax - a retrospective study.BMC pulmonary medicine · 2019Article
- The Role of Chest Computed Tomography in the Evaluation and Management of the Patient with Chronic Obstructive Pulmonary Disease.American journal of respiratory and critical care medicine · 2017Review
- Erratum: Severity of pulmonary emphysema and lung cancer: analysis using quantitative lobar emphysema scoring: Erratum.Medicine · 2017Article
- Influence of the type of emphysema in the relationship between COPD and lung cancer.International journal of chronic obstructive pulmonary diseaseObservational
Corrections and comments
- Erratum issued
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this study was to determine the relationship between lobar severity of emphysema and lung cancer using automated lobe segmentation and emphysema quantification methods.This study included 78 patients (74 males and 4 females; mean age of 72 years) with the following conditions: pathologically proven lung cancer, available chest computed tomographic (CT) scans for lobe segmentation, and quantitative scoring of emphysema. The relationship between emphysema and lung cancer was analyzed using quantitative emphysema scoring of each pulmonary lobe.The most common location of cancer was the left upper lobe (LUL) (n = 28), followed by the right upper lobe (RUL) (n = 27), left lower lobe (LLL) (n = 13), right lower lobe (RLL) (n = 9), and right middle lobe (RML) (n = 1). Emphysema ratio was the highest in LUL, followed by that in RUL, LLL, RML, and RLL. Multivariate logistic regression analysis revealed that upper lobes (odds ratio: 1.77; 95% confidence interval: 1.01-3.11, P = 0.048) and lobes with emphysema ratio ranked the 1st or the 2nd (odds ratio: 2.48; 95% confidence interval: 1.48-4.15, P < 0.001) were significantly and independently associated with lung cancer development.In emphysema patients, lung cancer has a tendency to develop in lobes with more severe emphysema.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.