ArticleMedicine2016
Short-term hypertension management in community is associated with long-term risk of stroke and total death in China: A community controlled trial.
Article in Medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed.
- Effect of a Multicomponent Intervention Delivered on a Web-Based Platform on Hypertension Control: A Cluster Randomized Clinical Trial.JAMA network open · 2022Trial
- Effect of a Workplace-Based Multicomponent Intervention on Hypertension Control: A Randomized Clinical Trial.JAMA cardiology · 2020Trial
- The Roles of Electronic Health Records for Clinical Trials in Low- and Middle-Income Countries: Scoping Review.JMIR medical informatics · 2023Article
- Combined management can decrease blood pressure: an investigation of health-seeking behaviors among hypertensive patients in urban communities in China.BMC cardiovascular disorders · 2021Article
- Assessed and Emerging Biomarkers in Stroke and Training-Mediated Stroke Recovery: State of the Art.Neural plasticity · 2017Review
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIt is not fully clear whether the effect of short-term management in community can reduce the long-term risk of stroke
objectives: To evaluate whether short-term hypertension management is associated with long-term incidence of stroke and total death in community health centers in China.
designCommunity controlled trail.
participantsSix community health centers (4 active, 2 control) in China, patients with hypertension. CONTROL ARM: Patients were treated with normally therapy method. ACTIVE ARM: Patients were treated oriented by the Guideline for hypertension management. RANDOMIZATION: Two centers (Hebei and Zhejiang) from the Hypertension Control in Community (HCC) Project, which was conducted from 2005 to 2008, were randomly selected for this study. Four thousand hypertensive patients from these centers, who were under management for one year in the baseline, were followed up in 2013. The electronic health record system (2005-2008) was used to identify 2000 hypertensive patients, who were not included in HCC but lived in comparable community health center in the same province, as the control group. All baseline and follow-up data were collected using standardized questionnaires for stroke outcomes.
main outcome measuresStroke.
resultsOf the 6000 participants, 3787 (63.1%) were eligible for analysis. At the time of follow-up, the average BP was kept in the lower level than that in baseline, and the control rate was 59.3%. After propensity-score matching, 110 strokes (2.0% vs 4.6%) and 141 deaths (1.4% vs 3.8%) were noted in the matched intervention and control groups (1078 pairs), respectively. Patients in the intervention group were less likely to experience a stroke or die than those in the control group (hazard ratio [HR] = 0.40, 95% confidence interval [CI]: 0.26-0.62, P < 0.01; HR = 0.50, 95% CI: 0.35-0.72, P < 0.01). The sensitivity analysis showed similar results.
conclusionsShort-term management of hypertension had a positive effect on the long-term risk reduction of death and stroke in hypertensive patients.
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