Evidence map›Paper›PMID 27902542›Full record

Observational studyJournal of developmental and behavioral pediatrics : JDBP2017

Impact of Mental Health Comorbidities on the Community-Based Pediatric Treatment and Outcomes of Children with Attention Deficit Hyperactivity Disorder.

Nour Al Ghriwati, Joshua M Langberg, William Gardner, James Peugh, Kelly J Kelleher, Rebecca Baum, William B Brinkman, Phil Lichtenstein, Jeffery N Epstein

Abstract readObservational Study
In one paragraph

Observational study in Journal of developmental and behavioral pediatrics : JDBP, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Nour Al Ghriwati*Department of Psychology, Virginia Commonwealth University, Richmond, VA; †Research Institute, Children's Hospital of Eastern Ontario, Ottawa, Ontario; ‡Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH; §Department of Pediatrics, Nationwide Children's Hospital, Columbus, OH; ‖The Children's Home of Cincinnati, Cincinnati, OH.
Joshua M Langberg
William Gardner
James Peugh
Kelly J Kelleher
Rebecca Baum
William B Brinkman
Phil Lichtenstein
Jeffery N Epstein

Funding

LCenter for Clinical and Translational Science and TrainingUL1TR001425 · NCATS · UNIVERSITY OF CINCINNATI · PI HEUBI, JAMES E., KISSELA, BRETT M · 2015 to 2024
$37.5M
Cincinnati Center for Clinical and Translational Sciences and TrainingUL1TR000077 · NCATS · UNIVERSITY OF CINCINNATI · PI HEUBI, JAMES E. · 2012 to 2014
$9.9M
Evaluation of an Intervention for Improving Community-Based Pediatric ADHD CareR01MH083665 · NIMH · CINCINNATI CHILDRENS HOSP MED CTR · PI EPSTEIN, JEFF N. · 2010 to 2014
$2.5M
Examining the Biological Basis of ADHDK24MH064478 · NIMH · DUKE UNIVERSITY · PI EPSTEIN, JEFF N. · 2002 to 2014
$1.4M
Medication Continuity in Children Treated for ADHDK23MH083027 · NIMH · CINCINNATI CHILDRENS HOSP MED CTR · PI BRINKMAN, WILLIAM BERNARD · 2010 to 2014
$878k
NCATS NIH HHS UL1 TR000077NCATS NIH HHS UL1 TR001425NIMH NIH HHS K23 MH083027NIMH NIH HHS K24 MH064478NIMH NIH HHS R01 MH083665
6 · The paper itself

Abstract

objectiveChildren with attention deficit hyperactivity disorder (ADHD) often exhibit psychiatric comorbidities, which may impact illness presentation, diagnosis, and treatment outcomes. Guidelines exist for dealing with these complex cases but little is known about how comorbidities are being handled in community pediatric settings. The purpose of this study was to evaluate how mental health comorbidities affect community physicians' ADHD care practices and patients' symptom trajectories.

methodMedical charts of 319 children presenting at primary care clinics for ADHD-related concerns were reviewed. Physician assessment and treatment behaviors were extracted and parents rated ADHD symptoms at the time of diagnosis and at 3, 6, and 12 months. Baseline ratings were used to group children, as no comorbid mental health condition, internalizing, or externalizing comorbid condition. Multilevel analyses compared community physician care behaviors and ADHD symptom trajectories across groups.

resultsApproximately, 50 percent of the sample met screening criteria for a comorbid mental health condition. For children diagnosed with ADHD and treated with medication, community physician care largely did not differ across groups, but children with internalizing comorbidities made significantly smaller improvements in inattentive and hyperactive/impulsive symptoms compared with children with no comorbidities.

conclusionChildren with ADHD and mental health comorbidities, particularly internalizing disorders, exhibit less robust response to ADHD medication and may require additional testing before starting medication and/or alternative treatment approaches. Potential barriers to conducting comprehensive assessments and to providing multi-modal treatment are discussed.

Indexed as

Mental DisordersAdultAttention Deficit Disorder with HyperactivityChildCommunity Health ServicesComorbidityFemaleFollow-Up StudiesHumansMaleMiddle AgedOutcome and Process Assessment, Health CarePractice Patterns, Physicians'

Identifiers

PMID27902542
PMCPMC5198773

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.