Evidence map›Paper›PMID 27901633›Full record

ArticleHuman vaccines & immunotherapeutics2017

Acute flaccid paralysis laboratorial surveillance in a polio-free country: Brazil, 2005-2014.

Ivanildo P Sousa, Fernanda M Burlandy, Silas S Oliveira, Amanda M Nunes, Cristiane Sousa, Elaine M da Silva, Jaqueline G A Souza, Valdemar A de Paula, Ivone C M Oliveira, Fernando Neto Tavares and 2 more

Abstract read
In one paragraph

Article in Human vaccines & immunotherapeutics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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  11. Strengthening Acute Flaccid Paralysis Surveillance Through the Village Polio Volunteers Program in Somalia.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Ivanildo P Sousaa Laboratório de Enterovírus , Instituto Oswaldo Cruz, Fundação Oswaldo Cruz , Rio de Janeiro , Brazil.
Fernanda M Burlandya Laboratório de Enterovírus , Instituto Oswaldo Cruz, Fundação Oswaldo Cruz , Rio de Janeiro , Brazil.
Silas S Oliveiraa Laboratório de Enterovírus , Instituto Oswaldo Cruz, Fundação Oswaldo Cruz , Rio de Janeiro , Brazil.
Amanda M Nunesa Laboratório de Enterovírus , Instituto Oswaldo Cruz, Fundação Oswaldo Cruz , Rio de Janeiro , Brazil.
Cristiane Sousaa Laboratório de Enterovírus , Instituto Oswaldo Cruz, Fundação Oswaldo Cruz , Rio de Janeiro , Brazil.
Elaine M da Silvaa Laboratório de Enterovírus , Instituto Oswaldo Cruz, Fundação Oswaldo Cruz , Rio de Janeiro , Brazil.
Jaqueline G A Souzaa Laboratório de Enterovírus , Instituto Oswaldo Cruz, Fundação Oswaldo Cruz , Rio de Janeiro , Brazil.
Valdemar A de Paulaa Laboratório de Enterovírus , Instituto Oswaldo Cruz, Fundação Oswaldo Cruz , Rio de Janeiro , Brazil.
Ivone C M Oliveiraa Laboratório de Enterovírus , Instituto Oswaldo Cruz, Fundação Oswaldo Cruz , Rio de Janeiro , Brazil.
Fernando Neto Tavaresb Laboratório de Enterovírus, divisão de virologia , Instituto Evandro Chagas , Belém , Brazil.
Eliane V da Costaa Laboratório de Enterovírus , Instituto Oswaldo Cruz, Fundação Oswaldo Cruz , Rio de Janeiro , Brazil.
Edson Elias da Silvaa Laboratório de Enterovírus , Instituto Oswaldo Cruz, Fundação Oswaldo Cruz , Rio de Janeiro , Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The last case of paralytic poliomyelitis caused by wild poliovirus in Brazil occurred in 1989. The interruption of the indigenous poliovirus transmission was obtained through mass immunization campaigns to eligible children and an active epidemiological and laboratorial surveillance of all cases of acute flaccid paralysis (AFP) among children under 15 y of age. This paper describes and evaluates the performance of the AFP surveillance system in different geographic areas of Brazil between 2005 and 2014, using indicators recommended by WHO. AFP surveillance indicators as well as virological investigation of polio and non-polio enteroviruses in stool samples received in the laboratory were assessed from 2005-2014. During the period, 5463 cases of AFP were investigated. Of these, 55% were males and 45% were females. Those under 5 y of age represented 48% of all cases reported and investigated. AFP notification rate was within the acceptable values with mean value of 1.3 (North), 1.4 (Northeast), 1.1 (Southern), 1.0 (Southeast) and 1.4 (Midwest) cases of AFP per 100.000 population aged 15 y as well as the adequacy of fecal specimens received in the laboratory. Sabin- related polioviruses accounted for 1.7% of the isolates while, 6.7% were non-polio enterovirus with the values ranging from 5.0% to 8.9 %. No wild-type polio was found. The AFP epidemiological and laboratorial surveillance activities have been kept at appropriate levels in Brazil. These data are a very strong indication, which supports the status of country free of polio.

Indexed as

Epidemiological MonitoringAdolescentBrazilChildChild, PreschoolEnterovirusFecesFemaleHumansIncidenceInfantInfant, NewbornMaleParaplegiaRetrospective Studiesacute flaccid paralysisenterovirusglobal polio eradication initiativepoliovirussurveillance

Identifiers

PMID27901633
PMCPMC5360118

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.